In summary, the overall blastocyst quality, and the TE and ICM grades were shown by the present study to be closely and positively associated with patient pregnancy outcomes during single euploid
blastocyst transfer cycles.
The literature contains 2 additional studies that incidentally report data allowing the computation of the ectopic pregnancy rate with
blastocyst transfer without any information on day 3 transfers.
Single
blastocyst transfer (SBT), widely used in Europe, guarantees a reduction in multiple births, the biggest problem facing fertility specialists worldwide.
"We feel strongly that single
blastocyst transfer is the way to go," said Marius Meintjes, Ph.D., scientific director of assisted reproductive technology services at Presbyterian Hospital of Dallas.
Multiple gestations in assisted reproductive technology: can they be avoided with
blastocyst transfers? Am J Obstet Gynecol 184:1471-1477.
"The chance of pregnancy increases from 12 to 15 per cent using current techniques to 25 to 30 per cent of women who use
blastocyst transfer," said Dr Steward.
Trophectoderm morphology: an important parameter for predicting live birth after single
blastocyst transfer. Hum Reprod.
Comparison of
blastocyst transfer with and without preimplantation genetic diagnosis for aneuploidy screening in couples with advanced maternal age: a prospective randomized controlled trial.
(2) Before the mid-1990s, low production and accompanying low viability of blastocysts during human IVF due to the inability of any single culture medium to meet and sustain the changing nutritional requirements of preimplantation embryos resulted in
blastocyst transfer being abandoned.
Influence of BMI on risk of miscarriage after single
blastocyst transfer. Hum Reprod 2011;26:2642-50.
(2012) assessed 2150
blastocyst transfer cycles which illustrated more pregnancy rate in frozen-thawed group, because of hormonal stimulation as the factor reduces embryo acceptance capacity of endometrium, (11) and also, Chunjuan et al.
Single
blastocyst transfer: a prospective randomized trial.