Bladder tumor antigen | definition of bladder tumor antigen by Medical dictionary
bladder tumor antigen
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bladder tumor antigen Abbreviation: BTA
A protein released into the urine by malignant cells in the bladder, studied as a possible marker of cancer of the urinary bladder. Because of the low prevalence of bladder cancer in the population at large, and the low positive predictive value of the test, the U.S. Preventive Services Task Force (2006) discouraged health care professionals and patients from using this screening test.
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References in periodicals archive
a variety of markers have been developed, and the following have been approved by the Food and Drug Administration to monitor patients with bladder cancer: bladder tumor antigen
(BTA), fibrin/fibrinogen degradation product (FDP), and nuclear matrix protein (NMP22).
A comparison of urinary nuclear matrix protein-22 and bladder tumor antigen
tests with voided urinary cytology in detecting and following bladder cancer: the prognostic value of false-positive results.
Among these, Food and Drug Administration (FDA) approval for monitoring of patients with bladder cancer has been given to nuclear matrix protein (NMP) 22, fibrin /fibrinogen degradation product (FDP), and bladder tumor antigen
(BTA; Table 1).