biphosphonate

Endocrinology Any of a number of carbon-substituted analogues of pyrophosphate, an endogenous inhibitor of bone mineralization Indications Malignant hypercalcemia, Paget's disease, breast and prostate CA, myeloma; the most potent is zoledronic acid, which can be given at intervals of up to one yr Adverse events Oral–GI intolerance; IV–myalgia, pyrexia. See Osteoporosis.

References in periodicals archive ?

Fortunately neither has ruled out suitable exercise, so with veterinary support, local injection steroids, systemic biphosphonate and careful management, the 11-year-old gelding continues to enjoy an active life with lunging and schooling to keep him supple.

Only Paddy displays genuine endurance

This has been seen in a patient undergoing chemotherapy or biphosphonate treatment including reduction of some of the undesirable side effects of the treatments (33).

Cancer in North Cyprus: 1. Current Status, An Overview

The patient had chronic medical conditions that favored a parenteral therapy over an oral biphosphonate.

Stroke following zoledronic acid infusion: effect of treatment or coincidence?/Zoledronik asit infuzyonu sonrasi gelisen inme: Tedavinin yan etkisi mi tesaduf mu?

In 2003, Marx first identified osteonecrosis of the jaw associated with biphosphonate therapy.

Bisphosphonate-related osteonecrosis of the jaw

This is another biphosphonate that has been approved by the FDA for prevention and treatment of osteoporosis in postmenopausal women.

Osteoporosis

1) Zoledronic acid (aclasta) is an annual biphosphonate IV infusion given over 15-30 minutes.

Primary health care nurses take on new challenges: opportunities for innovation in primary care are increasing. Nurses at one North Island practice are now delivering aclasta infusions, a procedure traditionally performed in hospitals

They were also given a sodium biphosphonate enema to be used the morning of the procedure to ensure adequate bowel preparation.

A prospective study on pain score with transperineal prostatic gold seed fiducial implantation under local anesthetic alone

2005) examined the long-term effects of WBV on osteoporotic women who received alendronate, a biphosphonate drug used for osteoporosis.

Whole-body vibration and rehabilitation of chronic diseases: a review of the literature

It has been shown recently that a biphosphonate incorporated on to titanium implants increased bone density locally in the peri-implant region.

Surface characteristics of titanium dental implants for rapid osseointegration

For example, 'disease mongering' - Osteopenia, once considered a non-disease state in patients who had not lost enough bone density to be diagnosed with osteoporosis, has now turned into a disease itself, tryin gto convince physicians and patients that biphosphonate drug treatment will prevent their 'disease' from progressing.

Inverse benefits of drug marketing affect patient safety, public health

Biphosphonate incadronate inhibits growth of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells by interfering with the mevalonate pathway.

Endocrine and metabolic disorders in HTLV-1 infected patients

There are a few data on the benefit of anti-tumor necrosis factor-alpha and biphosphonate therapy on BMD in AS (6, 7).

Relationship between bone mineral density and disease activity in patients with ankylosing spondylitis / Ankilozan spondilitli hastalarda kemik mineral yogunlugunun hastalik siddeti ile iliskisi