biphenotypic leukaemiaA clonal expansion of 2 or more leukocyte populations, which occur in up to one-third of adult leukaemias with lymphoid and myeloid differentiation.
BLs have fewer complete remissions (30% for biphenotypic vs 70% for pure lymphocytic leukaemias) and reduced survival (8 vs 26 months). ALLs that co-express myeloid antigens have a poor prognosis.
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