biphenotypic leukaemia

biphenotypic leukaemia

A clonal expansion of 2 or more leukocyte populations, which occur in up to one-third of adult leukaemias with lymphoid and myeloid differentiation.

Prognosis
BLs have fewer complete remissions (30% for biphenotypic vs 70% for pure lymphocytic leukaemias) and reduced survival (8 vs 26 months). ALLs that co-express myeloid antigens have a poor prognosis.
Mentioned in ?
References in periodicals archive ?
Leukaemias under this category were given many different names, including bilineage leukaemias, biphenotypic leukaemias, hybrid leukaemias, undifferentiated leukaemias.