biosynthetic pathway


Also found in: Dictionary, Thesaurus, Legal, Encyclopedia.

pathway

 [path´wa]
a course usually followed. In neurology, the nerve structures through which a sensory impression is conducted to the cerebral cortex (afferent pathway), or through which an impulse passes from the brain to the skeletal musculature (efferent pathway). Also used alone to indicate a sequence of reactions that convert one biological material to another (metabolic pathway).
accessory pathway (accessory conduction pathway) extra muscle tissue between the atrium and ventricle that bypasses all or part of the normal conduction system. When the ventricles are activated prematurely via this pathway, initial forces are slow, producing the delta wave of wolff-parkinson-white syndrome, and preexcitation is said to exist; the delta wave causes the PR interval to shorten and the QRS interval to broaden.
alternative complement pathway see complement.
amphibolic pathway a group of metabolic reactions with a dual function, providing small metabolites for further catabolism to end products or for use as precursors in synthetic, anabolic reactions. The tricarboxylic acid cycle is an example. See also anabolism and catabolism.
biosynthetic pathway the sequence of enzymatic steps in the synthesis of a specific end-product in a living organism.
classical complement pathway see complement.
common pathway of coagulation the steps in the mechanism of coagulation (see clotting) from the activation of factor x through the conversion of fibrinogen to fibrin. See also intrinsic pathway of coagulation and extrinsic pathway of coagulation.
concealed accessory pathway an accessory pathway that has only retrograde conduction; thus its PR and QRS complexes are normal on the electrocardiogram, but there is a tendency to develop premature supraventricular tachycardia. If atrial fibrillation develops, conduction will proceed across the atrioventricular node.
Embden-Meyerhof pathway the series of enzymatic reactions in the anaerobic conversion of glucose to lactic acid, resulting in energy in the form of adenosine triphosphate (ATP).
extrinsic pathway of coagulation the mechanism that produces fibrin following tissue injury, beginning with formation of an activated complex between tissue factor and factor vii and leading to activation of factor x, which induces the reactions of the common pathway of coagulation. See also intrinsic pathway of coagulation.
final common pathway
1. the motor neurons by which nerve impulses from many central sources pass to a muscle or gland in the periphery.
2. any mechanism by which several independent effects exert a common influence.
intrinsic pathway of coagulation a sequence of reactions leading to fibrin formation, beginning with the contact activation of factor xii. This is followed by the sequential activation of factors xi and ix, which results in the activation of factor x. Activated factor X (factor Xa) initiates the common pathway of coagulation. See also extrinsic pathway of coagulation.
pentose phosphate pathway a pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, the final forming a pentose phosphate.

biosynthetic pathway

The chemical and metabolic events that lead to the formation of substances in the body.
See also: pathway

pathway

a course usually followed. In neurology, the nerve structures through which a sensory impression is conducted to the cerebral cortex (afferent pathway), or through which an impulse passes from the brain to the skeletal musculature (efferent pathway). Also used alone to indicate a sequence of reactions that convert one biological material to another (metabolic pathway).

biosynthetic pathway
the sequence of enzymatic steps in the synthesis of a specific end product in a living organism.
coagulation p's
see coagulation pathways.
Embden-Meyerhof pathway
final common pathway
1. the motor neurons by which nerve impulses from many central sources pass to a muscle or gland in the periphery.
2. any mechanism by which several independent effects ultimately exert a common influence.
pentose phosphate pathway
a pathway of hexose oxidation in which glucose-6-phosphate undergoes two successive oxidations by NADP, each producing NADPH, the final forming a pentose phosphate.
properdin pathway
alternative complement pathway.
References in periodicals archive ?
This methodology has been used to determine the biosynthetic pathways of DON [9] and fumonisin [B.
Butamax's engineered biosynthetic pathway includes improvements to various enzymes of the pathway providing significant advancement in the low-cost production of biobutanol.
The idea that DHF might be involved in a plausible biosynthetic pathway to sugars (via a decarboxylative conversion to glycolaldehyde which aldolizes to sugars) dates back about as far as work on the formose reaction, but the experiments proved otherwise, causing DHF to fall from focus.
While the biosynthetic pathway by which ABA is formed remains obscure, the degradation pathway has been clearly established.
In this publication, the authors describe how, by using an untargeted metabolomic approach based on Metabolon's proprietary platform, the mode of action of GMX1778 was clearly identified to be in the inhibition of nicotinamide adenine dinucleotide (NAD+) biosynthetic pathway.
In this case, the enzyme subset is based on KARI enzymes having a modification that provides production efficiencies through the fundamental isobutanol biosynthetic pathway invented by Butamax.
This is especially true for the fundamental biosynthetic pathway claimed in our '188, '889 and related patents filed by Butamax several years ago," said Paul Beckwith, Butamax CEO.
They say that more than one biosynthetic pathway is usually involved in NAD+ production.
Objective 2) To ascertain the origin and localization of the main chemical compounds, coming either from a prey, or by establishing the biosynthetic pathway, on the basis of the nature of the chemicals and the putative trophic relationships.
These microorganisms are engineered with the isobutanol biosynthetic pathway invented by Butamax that includes five enzymatic steps that convert sugar to isobutanol.
By manipulating a key enzyme in the biosynthetic pathway for these compounds, researchers were able to produce a range of halogenated alkaloids that aren't produced in nature.
Because of this, its biosynthetic pathway offers potential as a novel therapeutic target and for future small molecule inhibitor screening and design.