Furthermore, they are now conducting TK, PK/PD, and physiologically-based PK (PBPK) modeling bringing pharmacometrics and biosimulation into clinical trials.
We are just starting to see the profound impact that biosimulation, model-based meta-analysis, and comparative effectiveness analysis can have on a drug candidate's development, regulatory review, and clinical application.
ELLEN LEINFUSS, MBA, is a senior vice president at Certara, a global biosimulation and regulatory writing company, committed to optimizing drug development decisions.
QSP is an emerging biosimulation
discipline that combines computational modeling and experimental methods to examine the mechanistic relationships between a drug, the biological system, and the disease process.
The global biosimulation market is expected to reach USD 2,107.99 million by 2020 from USD 1,034.93 million in 2015, at a CAGR of 15.29% between 2015 and 2020.
North America is expected to account for the largest share in the global biosimulation market in 2015.
Through internal growth and acquisition, Princeton, NJ-based Certara has become a global leader in biosimulation
technology for drug development.
Certara is a global biosimulation
technology-enabled drug development company.
Delisting the shares effectively made this provider of biosimulation
models a private company.
Svenn Borgersen, principal consultant at his biomechanical analysis firm BIOSIMulations