biological safety cabinet

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biological safety cabinet

A term for an enclosed and ventilated workspace in a microbiology lab, which is designed to contain pathogens. They are classified according to the protection they provide and the pathogens they are equipped to handle.

Types, biological safety cabinets 
Class I—provide protection for personnel and environment, but not the specimen itself. The airflow may be ducted externally or filtered and exhausted back into the laboratory.

Class II—provide protection for both personnel and equipment as well as the specimen. They are subdivided into 4 types: A1, A2, B1, B2, which are defined by National Science Foundation International Standard 49.

Class III—deployed only in maximum-containment laboratories and specifically designed for Biosafety Level 4 (Hazard Group 4 in the UK) pathogens, which include agents that cause Bolivian and Argentine haemorrhagic fevers, Marburg virus, Ebola virus, Lassa fever, Crimean-Congo haemorrhagic fever, smallpox, and other haemorrhagic diseases.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The biosafety cabinet enables safe reconstitution of cancer drugs without exposing doctors to toxic fumes.
Standard 49 was also updated to clarify that chlorine dioxide gas, when used for space decontamination of biosafety cabinets, should be generated outside of the biosafety cabinet and introduced to the sealed interior via a delivery system.
The CellGard ES NU-480 Class II Biosafety Cabinet features an exclusive TouchLink LCD Control Center, energy-saving DC-ECM motor, sloped window, and longer HEPA filter life.
BSL 2 * Work is done in an open bench with precautions for splashes and aerosols (may include gloves, gowns, and biosafety cabinet).
The patient was infected by a unique strain used in an experiment performed partly outside a biosafety cabinet. Vaccination should continue to be recommended, but laboratories with unvaccinated workers should also implement more stringent biosafety practices.
Co-workers reported that the patient had performed slide agglutination testing and recorded colonial morphology using typical biosafety level 2 (BSL 2) precautions; this did not entail the use of a biosafety cabinet. PFGE was performed at the state public health laboratory and at CDC on all four specim ens handled by the microbiologist; results of this testing indicated that the isolates from the patient and from one of the recently handled laboratory samples were indistinguishable.
Because the samples will be tiny, they may be best analyzed inside a small, closed compartment known as a biosafety cabinet, or glove box, says Race.
Senior Products Engineer Jim Hunter and Product Manager Brian Garrett, two of the brains behind what's been appropriately dubbed the BSC no-brainer, have spoken in the past about the challenges of developing an entirely new type of biosafety cabinet. Since R&D's list of finalists was released in August of 2016, though, they've had to prepare an altogether new type of statement: one of acknowledgement of their team's success.
6) All work with gram-negative or gram-variable small rods or coccobacilli isolated from tissues, blood, bone marrow, bone, or synovial fluid exudates should be carried out in a biosafety cabinet until Brucella has been ruled out.
The dispensers also have a low bag opening, allowing more comfort and better ergonomics, especially when using in a biosafety cabinet. INTERSCIENCE, +33 1 34 62 62 61