bioreactor


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bioreactor

(bī′ō-rē-ăk′tər)
n.
An apparatus, such as a fermentation chamber, for growing organisms such as bacteria or yeast that are used in the biotechnological production of substances such as pharmaceuticals, antibodies, or vaccines, or for the bioconversion of organic waste.

bioreactor

A closed reaction vessel for fermentation or enzymatic reactions for production of cells and biosynthetic products, which range in size from benchtop fermentors to industrial tanks. Bioreactors allow automatic regulation of the flow of oxygen, culture medium and other nutrients, and maintaining the temperature and pH; they minimise the potential for contamination and can produce a higher density of cells than can be produced in traditional cultures; because of the limited mid-procedure cell access, bioreactors are of limited use in producing cells destined for cell therapy, for which culture bag systems are more popular.

bioreactor

a vessel in which a FERMENTATION or other BIOCONVERSION can be carried out, with controls for environmental conditions, such as temperature, pH and aeration. Bioreactors vary widely in terms of design and size. See also FERMENTER.
References in periodicals archive ?
The meeting will discuss the proposed construction of a new bioreactor landfill cell and a leachate storage and handling system.
It can be recalled that DOST's Industrial Technology Development Institute (ITDI) developed and introduced the bioreactor technology in 2000, which it designed to transform wastes into compost that can be used to grow vegetables and flowers and to propagate seed crops.
Utilizing this bioreactor system, manufacturers can attach a second rocking platform and Flexsafe RM TX bag to each BIOSTAT B control unit to scale-out their production.
With the scale-out strategy that WuXi Biologics pioneered in the industry to use multiple disposable bioreactors for commercial manufacturing, 4,000L CSRs will enable manufacturing up to the scale of 24,000L comparable to traditional stainless steel bioreactors yet still achieving the advantages of CAPEX and timeline reduction benefited from disposables.
Although the use of bioreactor to propagate viruses has been established, the propagation of vvIBDV using bioreactor system is poorly reported.
The bioreactor can be defined as a culture system in which there is a proper monitoring and control of culture variables such as pH, temperature, oxygen, and carbon dioxide concentration for the maintenance of a homogeneous physicochemical environment for the cells, as well as the support for cell adhesion (adherent cells) when needed.
The bioreactor was developed by Alessandra Balduini, an associate professor of biomedical engineering at Tufts University and molecular medicine at the University of Pavia in Italy, and David Kaplan, chair of biomedical engineering at Tufts.
1 -- The XCeed bioreactor system has been proven reliable and cost-effective in food and beverage, chemical and textile manufacturing, groundwater remediation, and refinery and petrochemical applications worldwide.
ISLAMABAD -- The US scientists have developed a next-generation platelet bioreactor to generate fully functional human platelets in the lab.
The deal will be instrumental to the development of Cell Therapy Limited (CTL) as Shijiazhuang, a listed Chinese company with a market capitalisation of around PS700m, makes the pump technology which is critical to the operation of a bioreactor machine necessary to produce the firm's heart failure treatment drug Heartcel.
According to the two companies, bioreactor treatment operating costs are among the lowest of any type of water treatment technology on the market today--with electron donor and solids handling representing a significant portion of long-term project costs.
Microbial Culture and Operation of the Bioreactor. The bioreactor was inoculated with 0.5 kg of activated sludge from Bani Malik Sewage Treatment Plant.