Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin
redox status: Insights from cells with tet-regulated GTP cyclohydrolase I expression.
Human monocytes/macrophages lack the enzyme 6-pyruvoyltetra-hydro biopterin
synthase, which converts N[H.
Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: Relative importance of the de novo biopterin
synthesis versus salvage pathways.
Reduced infectivity of a Leishmania donovani biopterin
transporter genetic mutant and its use as an attenuated strain for vaccination.
show that in the chronic fatigue/chronic Lyme disease patient, biopterin
(BH4) levels are low compared with normal controls.
Richardson MA, Read LL, Reilly MA, et al Analysis of plasma biopterin
levels in psychiatric disorders suggests a common BH4 deficit in schizophrenia and schizoaffective disorder.
Ari Sutu Vitaminler, aminoasitler, sekerler ve biopterin
Urinary excretion of biopterin
and neopterin in psychiatric disorders.
Effective methylation in the liver is also important and may be achieved by supplementing with B vitamins, particularly folate, as this may have an effect on the rate of biopterin
5), which may be due to the observation that (R)-NMSal deleted the allostery of tyrosine hydroxylase to biopterin
and limited catecholamine synthesis (10).
Folate deficiency, biopterin
and monoamine metabolism in depression.
A standard curve of biopterin
dissolved in 6mM phosphate buffer (pH 7.