biomarker

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marker

 [mahr´ker]
something that identifies or that is used to identify; see also determinant.
cell-surface marker an antigenic determinant found on the surface of a specific type of cell.
tumor marker a biochemical substance indicative of presence of a tumor; ideally, it should be specific, sensitive, and proportional to tumor load. Called also biomarker.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

biomarker

(bī-ō-mark'ĕr),
A detectable cellular or molecular indicator of exposure, health effects, or susceptibility, which can be used to measure the absorbed, metabolized, or biologically effective dose of a substance, the response to the substance including susceptibility and resistance, idiosyncratic reactions, and other factors or conditions.
Farlex Partner Medical Dictionary © Farlex 2012

biomarker

(bī′ō-mär′kər)
n.
1. Medicine
a. A physiological substance, such as human chorionic gonadotropin or alpha-fetoprotein, that when present in abnormal amounts in the serum may indicate the presence of disease, as that caused by a malignancy.
b. A specific physical trait used to measure or indicate the effects or progress of a disease or condition: Biomarkers of aging include thinning of the hair. Also called biosignature.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

biomarker

(1) A characteristic which is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes or pharmacologic responses to a therapeutic intervention.
(2) A molecular indicator of a specific biological property or function that can be measured in blood or other body fluids or tissues; a biochemical feature or facet that can be used to suggest the presence of a particular disease, measure its progress or the effects of treatment.
 
Examples
PSA for prostate cancer, Hb1a for glucose control in diabetics, troponin I for acute MI.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

biomarker

Diagnostic medicine Any relatively specific biochemical parameter–eg, PSA, Hb1a or troponin I which, when found in ↑ amount in the blood, other body fluids, or tissues, suggest the presence of certain diseases or cancers. See Cardiac marker, Tumor marker.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

bi·o·mark·er

(bīō-mahr-kĕr)
A detectable cellular or molecular indicator of exposure,health effects, or susceptibility, which can be used to measure the absorbed, metabolized, or biologically effective dose of a substance, the response to the substance including susceptibility and resistance, idiosyncratic reactions, and other factors or conditions.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Biomarker

A biochemical substance that can be detected in blood samples and indicates the presence of a cancerous tumor.
Mentioned in: Ovarian Cancer
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

bi·o·mark·er

(bīō-mahr-kĕr)
A detectable cellular or molecular indicator of exposure, health effects, or susceptibility, which can be used to measure the absorbed, metabolized, or biologically effective dose of a substance, the response to the substance including susceptibility and resistance, idiosyncratic reactions, and other factors or conditions.
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about biomarker

Q. what is a safe tumor marker number range?

A. depends on the marker...most of the markers are materials that found normally in our body. and there are a number of markers and their levels differentiate. what marker do you mean?

Q. My wife(53) has elevated CEA and CA19.9 levels - near 150, without any concomitant reason/observation? Comment

A. Hi Bobby3,

The most important question is why were these tests done?
An elevated level may result from many causes, some of them are simple and some are more problematic. IMHO the best thing would be consulting her doctor to consider the need to check-up her alimentary system.
You can read more here (http://www.ascocancerfoundation.org/patient/ASCO+Resources/Patient+Guides/ASCO+Patient+Guide:+Tumor+Markers+for+Gastrointestinal+Cancers) and here (http://www.cancer.gov/cancertopics/factsheet/Detection/tumor-markers)

More discussions about biomarker
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References in periodicals archive ?
cancer biomarkers market, by application, 2014 - 2025 (USD Billion)
The new platform is built on a responsive micro-service oriented architecture and is powered by a state-of-the-art technology stack -- the result: enhanced functionality that connects biomarker data with analytics and an intuitive user experience.
Recently discovered biomarkers have been utilized to enhance the diagnosis of gastric cancer.
NEOMED said the merger of NEOMED-LABS and Pacific Biomarkers creates an expanded business with a broad set of capabilities, allowing the combined entity to better serve customers.
Comment: Pacific Biomarkers merged with existing portfolio company Neomed-LABS
Although hundreds of papers in nutrition are published annually, there is no current ontology for the area, no generally accepted classification terminology for biomarkers in nutrition and health, no systematic validation scheme for these biomarker classes and no recent systematic review of all proposed biomarkers for food intake.
In the Molecular Biosensing for Medical Diagnostics group at Eindhoven University of Technology, under the guidance of Professor Menno Prins, a sensing technology has been developed that enables the super-sensitive measurement of biomarker concentrations over time.
Biomarker qualification may occur during the drug approval process or by requesting regulatory qualification of a biomarker from the FDA's Center for Drug Evaluation and Research Biomarker Qualification Program.
Cancer biomarkers passes through a series of phases before they are used in clinical practice.
Visit Non-alcoholic Steatohepatitis Biomarkers Market by Biomarker Type (Apoptosis Biomarkers, Hepatic Fibrosis Biomarkers, Oxidative Stress Biomarkers, Serum Biomarkers) and End User (Academics and Research Institute, Diagnostic Laboratories, Pharma and CROs, and Hospitals) and Forecast 2017-2021 at https://www.ihealthcareanalyst.com/report/non-alcoholic-steatohepatitis-biomarkers-market/.
In the present study, analysis of results from one of the human clinical trials is further explored with a focus on the effect of curcumin on blood, urinary and salivary biomarkers, and on the potential role of biomarkers to predict treatment results.
Biomarkers of Brain Injury and Neurological Disorders