bioluminescent reporter

bioluminescent reporter

A cell genetically engineered to emit light when introduced into a test animal. Reporter systems have made great contributions to the study of eukaryotic gene expression and regulation; they are most frequently used as indicators of transcriptional activity.

Examples
Bacteria, fungi, tumour cells.
References in periodicals archive ?
In indirect labeling of EVs with a fluorescent protein (GFP/RFP) [23, 72], the same method is used as that for bioluminescent reporter proteins.
2005) or have used a bioluminescent reporter (such as luciferase) that has limited spatial resolution (Ciana et al.
Topics include staining and visualization of beta-galactosidase in mouse embryos and tissues, immunohistochemical detection of beta-galactosidase or green fluorescent protein on tissue sections, reporter gene expression in murine airways, 3D analysis of molecular signals with episcopic imaging techniques, fluorescent proteins for cell biology, detection of green fluorescent protein during nervous system developments in Drosophila melanogaster, autofluorescent proteins for flow cytometry, fluorescent protein reporter systems for single-cell measurements, subcellular imaging of cancer cells in live mice, noninvasive imaging of molecular events with bioluminescent reporter genes in living subjects and green fluorescent protein as a tracer in chimeric tissues.
Bagci-Onder will generate dual bioluminescent reporter systems of HRK and other TRAIL-associated factors, such as TRAIL receptors DR4/DR5; TRAIL signaling inhibitor proteins Flip, XIAP and Bcl-2 to assess gene expression changes.
Optical in-vivo imaging system for imaging of fluorescent and bioluminescent reporters in small animals, Plants and in-vitro samples.
Moreover, considering EGFP as a reporter has several advantages comparing to other bioluminescent reporters. In fact, the protein accumulation of EGFP as a reporter of gene expression could be directly observable in living cells.