biological readout

biological readout

A term of art referring to the result of a molecular interaction or gene activation—e.g., hair depigmentation as a readout for pharmacologic inhibition of the KIT receptor tyrosine kinase.
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These include "high content" screening (selecting compounds based on more complex biological readouts) and structural methods focused on the interaction of compounds with the target binding site (such as in silico approaches and fragment-based screening).
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