biological half-life


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biological half-life

n.
Biology The time required for one half of the total amount of a particular substance in a biological system to be degraded by biological processes when the rate of removal is nearly exponential
Nuclear physics The length of time required for one half of a radioactive substance to be biologically eliminated from the body

biological half-life

T1/2 Biology The time required for 1⁄2 of the total amount of a particular substance in a biologic system to be degraded by biological processes when the rate of removal is nearly exponential Radiation physics The length of time required for1/2 of a radioactive substance to be biologically eliminated from the body
References in periodicals archive ?
The physical half-life of caesium-137 is 30.22 years, whereas its biological half-life is 70 days.
Biological half-life of maternal enterovirus 71 neutralizing antibodies in 154 seropositive neonates, determined by crosssectional and longitudinal analyses, Taiwan * Antibody titers GMT at birth at 6 mo of age No.
One of the earliest toxicokinetics studies reported that Pb, once absorbed into the blood compartment, has a mean biological half-life of about 40 days in adult males (Rabinowitz et al.
However, in certain indications, some of their features can be detrimental: stimulation of the immune system via the antibody effector region; bivalent binding or crosslinking of the antigen; or the antibodies long biological half-life. XL-protein therefore decided to develop a monovalent antigen-binding antibody fragment (Fab) that does not bind immunoreceptors and promises fewer side-effects.
Further, in blood, DEHP is rapidly metabolized with a biological half-life in humans of < 6 hr (e.g., Peck and Albro 1982).