biological activity


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biological activity

the inherent capacity of a substance, such as a drug or toxin, to alter one or more chemical or physiological functions of a cell, tissue, organ, or organism. The biological activity of a substance is determined not only by the substance's physical and chemical nature but also by its concentration and the duration of cellular exposure to it. Biological activity may reflect a "domino effect," in which the alteration of one function disrupts the normal activity of one or more other functions.
References in periodicals archive ?
4 Ellagitannins An Underestimated Class of Plant Polyphenols: Chemical Reactivity of Cglucosidic Ellagitannins in Relation to Wine Chemistry and Biological Activity (Stphane Quideau, Michael Jourdes, Dorothe Lefeuvre, Patrick Pardon, Cdric Saucier, Pierre-Louis Teissedre, and Yves Glories).
The object of the contract includes delivery, installation, commissioning and training for operation of equipment for extraction, processing, analysis and sterilization of biological samples for the purposes of invitro laboratory to assess the biological activity and toxicity laboratory for the development and characterization of pharmaceutical forms and "in silico" design laboratory for extraction of natural products and synthesis of bioactive compounds in the "science and technology park", which is implemented under the operational programme "development of the competitiveness of the bulgarian economy 2007-2013" priority axis 1: "development an economy based on knowledge and innovation ", under a contract with id bg161po003-1.
The company hopes to patent its new technique, which combines analysis of all the active ingredients in the herb with tests for biological activity of the extract.
In the assessment of the biological activity of CGEN-241 as an antagonist of the HGF-Met pathway in various assays and model systems, the molecule demonstrated strong inhibition of multiple cellular functions related to this pathway, including cell proliferation, motility and invasion.
This free starch should be minimized since it can lead to biological activity, foam, deposits, poor specialty chemical efficiency, etc.
Biological activity at the base of the food chain in many regions of the ocean is limited by the availability of dissolved iron.
Guided by exploration of structural homology as a key to biological function, it was only a few years from the isolation of the first vertebrate sex steroid to the isolation of plant compounds with similar biological activity in castrated animals but not in the plant (42).
The molecules found in the rock, which left Mars some 15 million years ago, are being described as the fossil trace of past biological activity.
Angiogenesis Inhibitor, CT-322, Shows Biological Activity at First Dose Level Tested
The spherical and rod-shaped features in the Martian samples are rare but occur in patches, a pattern "highly suggestive of biological activity," she notes.