biochemical marker


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biochemical marker

[-kem′ikəl]
Etymology: Gk, bios + chemeia, alchemy
any hormone, enzyme, antibody, or other substance that is detected in the urine, blood, or other body fluids or tissues that may serve as a sign of a disease or other abnormality. An example is the Bence Jones protein that appears in the urine of multiple myeloma patients.

biochemical marker

Any biochemical compound such as an antigen, antibody, abnormal enzyme, or hormone that is sufficiently altered in a disease to serve as an aid in diagnosing or in predicting susceptibility to the disease.
See also: marker
References in periodicals archive ?
Although prediction includes a variety of outcome measures, in these models, ischemia is distinguished from controls by measuring biochemical markers involved in the ischemic cascade.
Instead, the clear message from this and several other sources is that biochemical markers of bone turnover/remodeling are very effective tools for monitoring the effectiveness of antiresorptive therapy in individual patients as well as in groups of patients.
Type I collagen is degraded during the bone resorption process, liberating small fragments, such as NTX, ([beta]-CTX, PYD, and DPD, into the blood and then into the urine (5, 31) and making serum and urinary concentrations of these fragments available as biochemical markers of bone resorption.
Can today's level of biochemical markers predict future bone density in the absence of pharmacologic intervention?
The study by Thomas and Thomas (1) convincingly demonstrates that biochemical markers are relatively insensitive in diagnosing functional iron deficiency.
The response profiles of the biochemical markers of bone turnover differ with different treatment protocols.
No other publication that I know of has such a comprehensive collection of clinical and technical information available on the current and future biochemical markers of MI.
To compare the performance of the biochemical markers, the ROC curves were estimated and the areas under these curves were calculated for every biochemical marker.
For those already suffering with chronic disease, once the biochemical markers are identified, strategies can be put in place to reverse chronic disease.
15,16 Use of biochemical markers of bone turnover is beneficial for assessing changes in BMD during anti resorptive treatment and in population studies of osteoporosis.
The scientists used magnetic resonance metabolic profiling to analyze the biochemical markers in the blood and urine of 61 patients with celiac disease, 29 with potential celiac disease, and 51 healthy people.

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