Instead, the clear message from this and several other sources is that
biochemical markers of bone turnover/remodeling are very effective tools for monitoring the effectiveness of antiresorptive therapy in individual patients as well as in groups of patients.
Characteristics of the traditional
biochemical markers listed in Figure 1 are well known, and assays to test for the existence of some of these markers are available (see Table 1).
Type I collagen is degraded during the bone resorption process, liberating small fragments, such as NTX, ([beta]-CTX, PYD, and DPD, into the blood and then into the urine (5, 31) and making serum and urinary concentrations of these fragments available as
biochemical markers of bone resorption.
Particulars of the subjects were recorded, about 3.0 ml venous blood was collected in plain gel tube for analysis of
biochemical markers. Gestational weeks were estimated by ultrasonography based on biparietal diameter and also matched with last menstrual period (LMP).
Capoccia et al.(11) investigated the relationship between serum levels of two
biochemical markers of cerebral injury, S100 protein and NSE, using postoperative diffusion-weighted magnetic resonance imaging, and neuropsychometric testing in patients undergoing CEA or carotid artery stenting (CAS).
Biochemical markers of bone formation (osteocalcin, OC) and resorption (carboxy-terminal collagen crosslinks, CTX) were measured in serum by an eletrochemioluminescence immunoassay preformed on an automated analyzer (Elecsys 2010, Roche Diagnostics[R]' Mannheim, Germany).
Biochemical markers in the assessment of bone disease.
The state of the skeleton can be evaluated by many techniques, of which
biochemical markers exhibit the fastest response to intervention while being minimally invasive (Watts, 1999).
Cerebral ischemia also initiates an inflammatory response in the brain and triggers the release of
biochemical markers into the blood.
(31) Increased lipolysis, the key
biochemical marker of lipodystrophy, causes increased flow of fatty acids to the liver, promoting the synthesis of triglycerides, reducing degradation of apolipoprotein B, and causing increased synthesis and secretion of VLDL-triglycerides.
The method involves directly detecting the presence of a
biochemical marker, specifically human glutamine synthetase, by immunoassay of bodily fluids.
This protein ratio can be a useful
biochemical marker for predicting the behaviour of different varieties in wheat-based products.
