Pharmaceutical scientists developing a drug with a biocatalytic
route often start with an existing enzyme.
Beasleyet al., "Biocatalytic
strategy toward asymmetric [beta]-hydroxy nitriles and [gamma]-amino alcohols," Tetrahedron Letters, vol.
Polyvalent metals such as iron can form very stable complexes by binding to multiple functional groups on one dissolved organic matter molecule and are perhaps the most versatile of the biocatalytic
elements (Peretyazhko & Sposito, 2006).
"We were particularly interested in the biocatalytic
process that leads up to the final compound," said Prof.
STEINER (2004): <<The Biocatalytic
Potential of Extremophiles and Extremozymes>>, Food Technology and Biotechnology, vol.
Soil-based gene discovery: A new technology to accelerate and broaden biocatalytic
preparation of acylated derivatives of flavonoid glycosides enhances their antioxidant and antimicrobial activity.
Catalytic and biocatalytic
oxidation of glucose to gluconic acid in a modified three phase reactor.
The patenting of research tools, protein design algorithms, and biocatalytic
processes, for example, are all frequently approached via process claims that embody, explicitly or otherwise, some manifestation of nature.
Membrane Reactors: Applications in Biotechnology and the Pharmaceutical Industry.
In some cases traditional organic/inorganic catalysts or stoichiometric reactions could be replaced by biocatalytic
(or enzymatic) routes, which offer environmental benefits.
Ultrasensitive aptamer-based protein detection via a dual amplified biocatalytic