To explore the influence of partitioning properties, we estimated CBATs for four hypothetical partitioning property combinations representing the range of potentially bioaccumulative
chemicals in the human food chain (Kelly et al.
The threats from persistent, bioaccumulative
and toxic chemicals are well-documented, said Jim Jones, assistant administrator in EPAs office of chemical safety and pollution prevention.
Parliament wants imported chemicals to be registered like those produced in the EU, but if they are part of finished articles, they would be exempted, unless they contain persistent bioaccumulative
substances or ones with endocrine disrupting properties.
Collins presented information on persistent, bioaccumulative
, and toxic substances and highlighted the link between sustainability and ethics.
In particular, industrial leather tanning entails significant use of: Hazardous substances during the tanning phase which end up in waste water; Fatliquoring products (used to re-introduce oil following tanning) which are generally not biodegradable; and Formulations containing volatile organic compounds (VOCs) or that generate persistent, bioaccumulative
and toxic (PBT) substances.
Currently there are no restrictions on any use of cVMS, but regulators in a number of countries are paying more attention to these compounds because of evidence they may be persistent, bioaccumulative
, and toxic.
The following are concerned: CMRs (substances that are carcinogenic, mutagenic and toxic to reproduction); PBT (persistent, bioaccumulative
and toxic substances); vPvB (very persistent and very bioaccumulative
substances); certain substances identified as having serious irreversible effects on humans or the environment, such as endocrine disrupters.
This will particularly apply to biocides, which are categorized as being persistent, bioaccumulative
and toxic (PBT).
As result, ministers "considered it appropriate to explore a possible extension of priority setting in the registration phase with the inclusion of potential PBTs and vPvBs" (persistent bioaccumulative
toxins and very persistent, very bioaccumulative
Section 199 gives similar authority, but is aimed specifically at a smaller list of substances defined as "CEPA-toxic" under Schedule I of CEPA (mainly substances that are persistent, bioaccumulative
The PBT Profiler will help pigment manufacturers to eliminate persistent, bioaccumulative
and toxic chemicals before they are fully developed, which will save companies R&D money and regulatory headaches, while lessening the burden on the EPA to test and retest suspect chemicals.
These chemicals are persistent and bioaccumulative
. Many perfluorochemicals are already classified as dangerous to human health and the environment.