Many bizarre cells were seen showing binucleation
or multinucleation, some resembling "wreath cells" or "horseshoe" or "donut-shaped" cells in the background of abundant lymphocytes, as shown in Figure 5.
5 Binucleated (BN) cell is most commonly present in cancer cells and may appear as a result of different type of causes; the increased rate of binucleation
is usually not preferably a definite indicative parameter.
Sings of regeneration was noticed in some areas as some cells showed mitotic activities and binucleation
Parameters that were analyzed in the smear (both cytosmear and modified brush biopsy samples) included enlarged nuclei, nuclear pleomorphism, nuclear borders, nucleocytoplasmic (N/C) ratio, number of nuclei, binucleation
, keratinization, tadpole forms, hyperchromatism, chromatin pattern, and distribution and discrepancy in N/C maturation.
Diabetic rat liver revealed moderate portal fibrosis (c) and binucleation
of the hepatocytes (d).
Polymorphs and pyknosis were seen on both the sides of buccal mucosa whereas micronuclei and binucleation
(Figure 6) were seen only in affected side after second week.
It includes karyorrhexis, karyolysis, micronucleus formation, pyknosis, binucleation
, broken-egg nucleus, anucleation, etc.
These abnormalities included marked binucleation
, anisokaryosis, karyolysis, karyorrhexis and karyopyknosis.
Histopathological evaluation criterias Cartilage Foreign-body Regenerative activity viability reaction (Score) (Environmental and cytoplasmic changes reaction) (Score) (Score) Completely None No changes, similar to Dead (0) (0) the literature (0) Partially Focal (1) Increase in Viable (1) the cytoplasmic vacuolization and eosinophilia (1) Viable Present Binucleation
and (2) (2) multi-nucleation (2) Widespread and destructive (3) TABLE 2.
The following are the criteria used for scoring the cell inclusions: (i) only cells with a distinct cytoplasm and distinct binucleation
were analyzed for the presence of MN, (ii) only MN entirely inside the cytoplasm, separated from the main nucleus and with a diameter <1/3 of the size of the main nucleus were scored, and (iii) only MN staining the same as or lighter than the nucleus were scored.
Cardiomyocyte DNA synthesis and binucleation
during murine development.
For liver, we analysed the centrality of nucleus, number of hepatocytes with binucleation
, congestion of central vein, leukocytes infiltration, number of kupffer cells and swelling lumen by the blood cells and congestion of sinusoids (Vieira et al.