grandiflorus at concentrations of 25, 50 and 80 [micro]g / mL of culture medium, there were no differences in the number of binucleate
cells with micronucleus between treatments with different doses of phytoterapic and the negative control (Fig.
(d) Granular immunoreactivity for Synaptophysin highlights dysplastic neurons, some of which are binucleate
In some of the specimens, regenerative changes such as anisocytosis and presence of binucleate
cells were also noted in the experimental animals.
The glycosylation of pregnancy-associated glycoproteins and prolactin-related protein-I in bovine binucleate
trophoblast giant cells changes before parturition.
Micronuclei, which are the primary cytological structures scored in the CBMN assay, are thought to contain chromatin (from one or more chromosomes) that was not incorporated ("lagging" or "lost") into the daughter binucleates
following nuclear division .
There were scattered apoptotic cells, few binucleate
cells, and multifocal areas of necrosis within the mass.
A microscopical study of uterine lining modification, binucleate
cell numbers and trophoblastic development, at 14, 20 and 24 of day gestation in single and multiple pregnancies in sheep.
CBPI was calculated as (number mononucleate cells + 2x number binucleate
cells + 3x number poiynucleate cells) + total number of cells.
Morphine sulfate ([10.sup.-4] M) alone had no effect on the observed frequency of micronucleated binucleate
cells, whereas mitomycin C (1.5 x [10.sup.-7] M) increased the frequency approximately 9-fold (Table 1).
(28) The binucleate
: mononucleate cell ratio may therefore prove to be an important biomarker for identifying individuals with a cytokinesis failure caused by higher-than-normal rates of aneuploidy, such as that observed in Down's syndrome.
Although much of the surface area of these placentas fits the epitheliochorial structure, large binucleate
cells from the trophectoderm migrate into the underlying endometrial epithelium and establish direct contact with the basement membrane.