bimatoprost


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bimatoprost

 [bĭ-mat´o-prost]
a synthetic prostaglandin analogue that acts as an ocular hypotensive; applied topically to the conjunctiva in the treatment of open-angle glaucoma and ocular hypertension.

bimatoprost

A synthetic PROSTAGLANDIN drug used as eye drops to control raised intraocular pressure in GLAUCOMA. A brand name is Lumigan.

prostaglandin analogues 

Drugs used in the treatment of open-angle glaucoma or ocular hypertension. At specific dosages they lower the intraocular pressure (IOP), supposedly by increasing the outflow of aqueous humour via the uveoscleral pathway. Common agents include latanoprost, travoprost, bimatoprost (a synthetic prostamide structurally related to prostaglandin) and unoprostone isopropyl. Bimatoprost reduces IOP by increasing the uveoscleral outflow as well as the trabecular outflow.
References in periodicals archive ?
A two-year comparative study by Cohen et al 2004 showed mean reduction of 7.8 mmHg with Bimatoprost and 4.6 mmHg with Timolol.(14)
Latisse - the "Botox for eyelashes", which has been developed from Bimatoprost - a medication used to treat eye disorders including glaucoma, is also being used by many actresses, including 'Man Men' star Christina Hendricks, Claire Danes and Brooke Shields.
Allergan received approval from the FDA for Lumigan (bimatoprost ophthalmic solution) 0.01% as a first-line therapy for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension.
Prostaglandin analogues in the market include: latanoprost, bimatoprost, and travoprost.
The Food and Drug Administration seized more than 12,000 tubes of a product claiming to increase eyelash growth because it was found to contain bimatoprost the active ingredient in a prescription glaucoma solution--that could potentially cause vision problems in users.
* Bimatoprost SR: Allergan reported positive topline results from two Phase 3 clinical trials of Bimatoprost SR, a first-in-class sustained-release, biodegradable implant for the reduction of intraocular pressure in patients with open-angle glaucoma or ocular hypertension.
Akorn (AKRX), up 6% after receiving an approval from the FDA for bimatoprost ophthalmic solution...
Other medications used after AFR to improve results include 5-fluorouracil, bimatoprost, and poly-L-lactic acid.
Prostaglandin analogs/prostamides such as bimatoprost were first approved in 1996 [10] but have become increasingly preferred as first-line options due to their efficacy, safety, and once-daily use [2, 10-14].