bilirubinuria


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Related to bilirubinuria: urobilinogen

bilirubinuria

 [bil″ĭ-roo″bĭ-nu´re-ah]
the presence of bilirubin in the urine, a sign of liver disease or duct obstruction.

bil·i·ru·bi·nu·ri·a

(bil'i-rū'bi-nyū'rē-ă),
The presence of bilirubin in the urine.
[bilirubin + G. ouron, urine]

bilirubinuria

(bĭl′ĭ-ro͞o′bə-no͝or′ē-ə)
n.
The presence of bilirubin in the urine.

bil·i·ru·bi·nu·ri·a

(bil'i-rū-bi-nyūr'ē-ă)
The presence of bilirubin in the urine.
[bilirubin + G. ouron, urine]

bil·i·ru·bi·nu·ri·a

(bil'i-rū-bi-nyūr'ē-ă)
The presence of bilirubin in the urine.
[bilirubin + G. ouron, urine]
References in periodicals archive ?
In malaria patients from Colombia, hemoglobinuria (86%), urobilinuria (66%), proteinuria (54%), hematuria (43%), and bilirubinuria (39%) were associated with dark urine; renal dysfunction was identified in these patients [7].
Hemoglobinuria, hematuria, and bilirubinuria have not been associated with liver or kidney dysfunction in previous observations in Colombia [7].
Dark urine was statistically related to bilirubinuria (OR 6.7, CI 1.6-6.0, P < 0.001), blood (OR 3.6, CI 1.9-5.2, P < 0.001), hemoglobinuria (OR 3.1, CI 1.5-6.0, P = 0.001), hematuria (OR 2.2, CI 1.2-3.9, P = 0.006), urobilinogen (OR 2.8, CI 1.6-5.0, P < 0.001), and proteins (OR 5.8, CI 3.5-9.7, P < 0.001).
Bilirubinuria. Present in 147 (24.3%) of 605 patients, bilirubinuria was associated with urobilinuria, proteinuria, and increased specific gravity (P < 0.05).
This alteration was associated with bilirubinuria, urobilinuria, blood, and increased specific gravity (P < 0.05) and was related to higher serum BUN, TB, DB, ALT, and aspartatetransaminase (AST) values and lower platelet counts.
Specific gravity was related to bilirubinuria (OR 1.7; CI 1.0-2.7; P 0.023), ketones (OR 2.3; CI 1.5-3.5; P 0.023), and proteins (OR2.3; CI 1.5-3.5; P < 0.001).
The most common urinalysis alterations in the 620 malaria patients were increased specific gravity (41.2%), proteinuria (39.2%), urobilinuria (30.6%), blood (29.8%), bilirubinuria (24.3%), ketones (22.7%), and leukocytes (14.86%).
Proteinuria [7, 10, 13, 14], hematuria [7, 11, 13], bilirubinuria [7, 11, 13], hemoglobinuria [7, 13, 25, 26], and myoglobinuria [10, 15, 16] have been found in the urinalysis of patients with malaria.
In our patients, proteinuria was associated with increased TB and DB serum levels, with increased risk of liver, kidney, and lung complications, and other alterations in urinalysis including bilirubinuria, urobilinuria, ketonuria, and glycosuria.
Bilirubinuria. The clinical manifestations of malaria generally include paroxysmal episodes of fever and chills every 24-48 hours or 72 hours depending on the infecting species [38, 39], which coincide with synchronous rupture of parasitized erythrocytes [3].
In these patients, both proteinuria (OR 1.5, CI 1.0-2.3) and bilirubinuria (OR 2.1, CI 1.3-3.3) were associated with an increased risk of liver complications; and both were related to renal complications (P < 0.05), suggesting a role as predictors of injury in these organs since kidney and liver dysfunction are involved in other clinical complications in malaria patients.
We, therefore, conclude that even though urinalysis is not an alternative diagnostic tool for malaria infection, urinary abnormalities, such as bilirubinuria, urobilinoge nuria, proteinuria and haematuria may help in identifying patients with severe malaria parasitaemia, especially the falciparum malaria.