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bile lakeAn extravasated pool of bile—cholestasis—lying outside of partially necrotic liver cell plates, which is caused by extrahepatic biliary obstruction and rupture of bile canaliculi.
a clear yellow, orange or green fluid produced by the liver. It is concentrated and stored in the gallbladder, and is poured into the small intestine via the bile ducts when needed for digestion. Bile helps in alkalinizing the intestinal contents and plays a role in the digestion and absorption of fat; its chief constitutents are conjugated bile salts, cholesterol, phospholipid, bilirubin and electrolytes. See also bile duct, biliary.
steroid acids derived from cholesterol; classified as primary, those synthesized in the liver, e.g. cholic and chenodeoxycholic acid, or secondary, those produced from primary bile acids by intestinal bacteria and returned to the liver by enterohepatic circulation, e.g. deoxycholic and lithocholic acid.
bile acid assay
are used in the diagnosis of liver disease and portacaval shunts when there are increased levels in the blood.
bile duct obstruction may cause distention and rupture of biliary canaliculi. Small bile lakes result causing focal hepatic necrosis.
bile canaliculi drain into bile ductules and interlobular ducts. These unite to form a series of hepatic ducts which carry the bile to the porta where they unite to form the common hepatic duct. This duct receives a cystic duct from the gallbladder (absent in the horse) and thence becomes the bile duct.
leakage of bile from the common bile duct or gallbladder may occur as a result of trauma, including perforation during percutaneous needle biopsy of the liver, and (rarely) erosion from biliary calculi. A chemical peritonitis results and may be fatal unless surgical repair is accomplished.
inflammation of the pleura resulting from perforating thoracic trauma with hepatodiaphragmatic fistula or iatrogenically from percutaneous liver biopsy techniques.
usually refers to movement of bile from the duodenum into the stomach where it may alter the gastric mucosal barrier causing gastritis and ulceration.
1. bile containing much mucin.
2. bile trapped in obstructed system for a long period and from which pigments have been resorbed.