bilateral prophylactic oophorectomy

The surgical excision of both ovaries in a woman at an increased risk of breast cancer because she carries the BRCA1 mutation, an effect attributed to reduction of ovarian hormone exposure.

References in periodicals archive ?

Effect of short-term hormone replacement therapy on breast cancer risk reduction after bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group.

Is menopausal hormone therapy safe when your patient carries a BRCA mutation?

It is interesting that some of these patients underwent bilateral prophylactic oophorectomy (BPO) and multivariate Cox analysis suggested that this led to a significant benefit in overall survival at 5 years.

Managing the contralateral breast in a gene mutation carrier with breast cancer

Breast cancer risk after bilateral prophylactic oophorectomy in BRCA1 mutation carriers.

Psychosocial factors that influence decision making about prophylactic surgery

While bilateral prophylactic oophorectomy offers protection against ovarian cancer, this option is limited to women beyond child-bearing age, some of whom do not consider this desirable outcome.

OCs Protect Women at High Risk for Ovarian Ca

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