biguanide


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Related to biguanide: metformin

biguanide

(bī-gwŏn′īd″)
A member of the class of oral antihyperglycemic agents that works by limiting glucose production and glucose absorption, and by increasing the body's sensitivity to insulin. Glucophage is one member of this drug class.
References in periodicals archive ?
In this study, Imeglimin will be administrated orally as a monotherapy or combination therapy with existing hypoglycemic agents, including a DPP4 inhibitor, SGLT2 inhibitor, biguanide, sulphonylurea and GLP1 receptor agonist.
In the present study, we can analyze that the solutions which containing polyaminopropyl biguanide (0.00013%), polyquaternium (0.0001%) and polyquaternium/ Polyquad (0.001%), and myristamidopropyl dimethylamine/ Aldox (0.0005%) have good disinfecting property against S.
Birnbaum, "Biguanides suppress hepatic glucagon signalling by decreasing production of cyclic AMP," Nature, vol.
Metformin (dimethyl biguanide) is the most widely used frontline drug for treatment of type II diabetes mellitus [1, 2].
PHMB (polyhexamethylene biguanide) is a water-soluble cationic disinfectant with wide clinical, household, and industrial applications [1-3], despite its poor optimal antibacterial effect.
Metformin (a biguanide, Figure 1) is the most extensively prescribed oral antidiabetic drug for the treatment of T2DM [2].
Perfect, "Scedosporium prolificans osteomyelitis in an immunocompetent child treated with voriconazole and caspofungin, as well as locally applied polyhexamethylene biguanide," Journal of Clinical Microbiology, vol.
Metformin is a biguanide that inhibits the formation of advanced glycation end products and reduces hepatic gluconeogenesis so it could be suggested that different extracts of plant might have inhibitory effect on the production of advanced glycation products and hepatic gluconeogenesis [11].
In the present study antibacterial activity of three commercially available disinfectants including Benzalkonium chloride (BZK), Polyhexamethylene biguanide (PHMB) and Glutaral C11-C15 Pareth 9 against Escherichia coli, Pseudomonas spp., Serratia spp.
Metformin is a biguanide derivate and has pleiotropic effects (1).
The product is the first solution formulated with natural ingredients such as polylysine as a disinfecting agent, instead of the usual polyhexamethylene biguanide (PHMB), as well as vitamin C glucoside and hyaluronic acid.
The marketed products landscape comprises a wide range of treatment options, including biguanide (metformin), sulfonylureas, thiazolidinediones, GLP-1 receptor agonist, DPP-4 inhibitor, SGLT-2 inhibitor, and insulin therapies.