FISH

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hybridization

 [hi″brid-ĭ-za´shun]
1. the production of hybrids.
fluorescent in situ hybridization (FISH) a genetic mapping technique using fluorescent tags for analysis of chromosomal aberrations and genetic abnormalities. Called also chromosome painting.
molecular hybridization in molecular biology, formation of a partially or wholly complementary nucleic acid duplex by association of single strands, usually between DNA and RNA strands or previously unassociated DNA strands, but also between RNA strands; used to detect and isolate specific sequences, measure homology, or define other characteristics of one or both strands.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

FISH

(fish),

fish

ichthyophobia.
Farlex Partner Medical Dictionary © Farlex 2012

fish

(fĭsh)
n. pl. fish or fishes
1. Any of numerous cold-blooded aquatic vertebrates characteristically having fins, gills, and a streamlined body and including the bony fishes, such as catfishes and tunas, and the cartilaginous fishes, such as sharks and rays.
2. Any of various jawless aquatic craniates, including the lampreys and hagfishes.
3. The flesh of such animals used as food.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
Cardiology Finnish Isradipine Study In Hypertension
Molecular medicine Fluorescent In Situ Hybridization. A method for locating a segment of DNA on a chromosome. The DNA is labeled with a fluorescent dye and hybridized to a cytological preparation of chromosomes that has been denatured to allow nucleic acid hybridization between chromosomal DNA and the probe. The site of hybridization is determined by fluorescent microscopy. FISH is a hybrid of 3 technologies: cytogenetics, fluorescence microscopy, and DNA hybridization, which is used to determine cell ploidy and detect chromosome segments by evaluating interphase—non-dividing—nuclei; in FISH, fluoresceinated chromosome probes are used for cytologic analysis and cytogenetic studies, and to detect intratumoral heterogeneity. In genetics, FISH provides a physical mapping approach to detect hybridization of probes with metaphase chromosomes and with the less-condensed somatic interphase chromatin
DNA probes may be applied to cell preparations on a slide; if the complementary DNA sequence is present, it binds to DNA and can be detected by light microscopy; FISH labels probes nonradioactively either directly with fluorochromes, or indirectly with biotin and fluorochrome-labeled avidin, with digoxeginin and fluorochrome-labeled anti-digoxeginin, or others; the use of multiple band-pass filters allows simultaneous viewing of numerous probes for different chromosomal sequences labeled with different fluorochromes; FISH is useful in cytogenetic studies, where probes for particular chromosomes—e.g., chromosomes 13, 18, 21—or chromosomal regions—e.g., ABL and BCR genes in the Philadelphia translocation—can be used for the prenatal diagnosis of common aneuploidies or to detect early stages of lymphoproliferative disorders; FISH is as sensitive as other analytical techniques—e.g., conventional cytology and flow cytometry, used to diagnose transitional cell carcinoma of the urinary bladder
Pros FISH is simpler, less labor-intensive, and time-consuming—48 hours—than classic cytogenetics—karyotyping—2-3 weeks
Cons Only one question can be asked at a time, i.e., rather than asking ‘global issues’—e.g., what is the genetic composition of a population of cells
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

FISH

Fluorescent in situ hybridization Molecular medicine A hybrid of 3 technologies: cytogenetics, fluorescence microscopy, and DNA hybridization, which is used to determine cell ploidy and detect chromosome segments by evaluating interphase–non-dividing nuclei; in FISH, fluoresceinated chromosome probes are used for cytologic analysis and cytogenetic studies, and to detect intratumoral heterogeneity. See Chromosomal paint box.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

FISH

Abbreviation for fluorescence in situ hybridization.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

FISH

Abbrev for fluorescence in situ hybridization. This is a technique for detecting and locating gene mutations and chromosome abnormalities.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

fish

any of a large group of cold-blooded, finned aquatic vertebrates. fish are generally scaled, and respire by passing water over gills. fish were formerly placed in a single grouping, class Pisces. It is now recognised that there are four distinct classes, ACTINOPTERYGII, (ray-finned fishes), CHOANICHTHYES (fins with central skeletal axis - collectively sometimes classed as Osteichthyes, see BONY FISH) CHONDRYCHTHYES (sharks) and APHETOHYIDEAN (extinct, primitive, jawed fish).

FISH

acronym for FLUORESCENCE IN SITU HYBRIDIZATION.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

FISH

(flourescence in-situ hybridization) Technique used to detect small deletions or rearrangements in chromosomes.
Mentioned in: Prader-Willi Syndrome
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

Patient discussion about FISH

Q. Does fish-oil helps exercise induced asthma? I was diagnosed with exercise induced asthma a couple of year ago, and since then had better and worse times with my asthma, although the treatment I get. I read in a newspaper that fish oil can help exercise induced asthma- is that true? Do I have to eat fish-oil specifically or can I eat fish instead (I really, really, hate fish-oil…)?

A. I take 6, 1000mg softgels/day. It helps my asthma, arthritis and has lowered my closterol. Started with 10 and worked down to 6, which seems to work best, though sometimes I need the extra.

Q. Can omega-3 make my cholesterol lower? My doctor told me that I have too much cholesterol in my blood, and that it can cause heart attack or stroke, but if I keep it low than my risk will be lower. He told me that because it’s not that high level I can try to change my diet before I have to start taking medication. I heard that omega-3 can make my cholesterol level low. Is that true? Do I have to take it in pills? Is it safe?

A. You can consume omega-3 either as pills or in fish oil, fatty fish (such as salmon) and vegetarian food such as flaxseed and flaxseed oil, canola oil, soybean oil, and nuts.

More discussions about FISH
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What you can expect at a Big Fish Little Fish family rave is not just top DJs playing club classics, but also bubble machines, club visuals, giant balloons and a giant parachute dance.
Color the big fish yellow, color the small fish orange.
For Bohn, certain spots might as well have neon signs with arrows pointing into the water: "Big Fish Here." That's where his lines have to be when civil twilight hits.
And it starts from a harsh challenge to the big fish: If your big contracts are so good for local authorities and the economies which surround them, prove it.
CATCH THEM: Reel Big Fish FESTIVAL WARM-UP: Kids In Glass Houses FRIENDS OF THE ENEMY: Up-and-coming trio The Kontours.
Tanaiste Mary Coughlan, who unveiled the IDAbacked investment, said: "This investment once again demonstrates Ireland is very much open for business and is positively viewed by international investors." Big Fish makes online games known as casual which do not require special skill and can be played in short bursts.
I was talking to a pal about Adams' decision and he said that Wolfie "clearly likes being a big fish in a small pond".
Not so with his Big Fish internet broadcast found at www.WhitefishRadio.com, launched January 8, 2007.
This is big fish country though the canal did not fish to form and winner Phil Walters (Liverpool AS) was first with 71b lloz of skimmer bream and roach, all caught on punch bread and an 11 metre pole.
Most of the rest of his family emigrated as well, but one brother, Shmiel, decided to return to the ancestral village and live as a "big fish in a small pond," rather than as a small fish in the ocean of America.
"The little fish will go in there for cover and to feed and the big fish will follow them," Missouri park ranger Eric Lemons told Reuters.
When a gifted program for classes 1 and 2 started, Groups 1 and 2 (the big fish) had higher self-concept than Group 4 (the small fish) but Group 2 did not score higher than Group 3.