reduced the maximum amplitude of [I.
infusions advance the timing of luteinizing hormone surge in proestrous rats: comparisons with naloxone effects.
insensitive GABA receptors: studies on the binding of (-)-baclofen to rat cerebellar membranes.
Identification of differential gene expression profiles in rat cortical cells exposed to the neuroactive agents trimethylolpropane phosphate and bicuculline
In various experiments these included bicuculline
, picrotoxin, Ro15-1788 (flumazenil) and delta-amino-n-valeric acid (Leslie, Shephard, & Toal, 1994; Shephard, Toal, & Leslie, 1990; Toal, Leslie, & Shephard, 1991).
(BIC) is a selective antagonist of GABA[sub]A R, which can inhibit the influence of chloride ions.
Spontaneous excitatory postsynaptic currents (sEPSCs) were recorded under voltage-clamp at -70 mV from CA1 pyramidal neurons after blocking the GABAA receptors by using 30 [micro]M bicuculline
A] antagonist, bicuculline
methiodide (BMI, 100, 200 pmol/100 nl; n=24 rats, injections=47; Sigma)
Antagonism of [gamma]-aminobutyric acid (GABA) receptors with bicuculline
(BIC) phenocopied the dendrite-promoting effects of PCB-95, and pharmacological antagonism or siRNA knockdown of RyR blocked BIC-induced dendritic growth in dissociated and slice cultures of hippocampal neurons.
was aliquoted in distilled water and diluted (1000-fold) in Ringer's to 10 [micro]M
Moreover, seizures induce IL-1 (3 release in cortex and hippocampus in bicuculline
rat model and further cause blood-brain barrier damage with protein extravasation (Li et al.
A] antagonist bicuculline
or the chloride channel blocker picrotoxin, and potentiated by 100 [[micro]molar] pentobarbital or 10 [[micro]molar] diazepam.