Composite low grade B-cell lymphomas with two immunophenotypically distinct cell populations are true biclonal
lymphomas: a molecular analysis using laser capture microdissection.
Clinical characteristics and outcomes in biclonal
Another possible mechanism to be considered is the presence of biclonal
population of tumor cells, with one clone harboring KRAS mutation and the other clone harboring BRAF mutation.
Almost four months after HCT, she developed progressive pancytopenia, biclonal
gammopathy, and IGH gene rearrangement.
Possible explanations may include a synchronous biclonal
origin (collision tumor)  and bidirectional or metaplastic differentiation of a single clone of totipotential cancer cells [4, 6, 9, 15].
Juge-Morineau et al analysed the immunoglobulin heavy chain V-region (Ig HV) genes of three IgD, one IgM, and one biclonal
(IgG and IgM) multiple myeloma for the presence of somatic mutations based on molecular analysis of the Ig HV.
gammopathy, defined as the simultaneous appearance of two different monoclonal protein components, is rare.
A surgical case of solitary plasmacytoma of rib origin with biclonal
Betticher, "Myelodysplastic syndrome with biclonal
monosomy 7 and trisomy 8 after treatment with cladribine (2-chloro-2deoxyadenosine) and involved field radiation therapy," Cancer Genetics and Cytogenetics, vol.
Pfeifer et al., "Biclonal
origin prevails in concomitant chronic lymphocytic leukemia and multiple myeloma," Leukemia, vol.
Under the continual stimulus of estrogen and progesterone, the smooth muscle cells continue to proliferate, eventually becoming biclonal
or monoclonal as individual cell types with growth advantages emerge.