OCA2

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OCA2

A gene on chromosome 15q11.2-q12 that encodes a protein which may be involved in tyrosine transport within melanocyte and play a role in regulating the pH of melanosomes and melanosome maturation, as well as in post-translational processing of tyrosinase, which catalyses the limiting reaction in melanin synthesis. OCA2 may serve as a key control point at which skin colour variation is determined; it is a major determinant of brown and/or blue eye colour.

Molecular pathology
Defects in OCA2  cause oculocutaneous albinism type 2, see there.
References in periodicals archive ?
Lacking the coercive infrastructure of the modern state, local rulers like the Ottoman beys of Tunis focused instead on creating urban institutions, fiscal rules, and security designed to facilitate the sale and transport of African goods (slaves, ostrich feathers, and gold) to European and Ottoman destinations.
Murray finished a drive and a Bey jumper in the lane made it 69-63 with under three minutes left.
In the gallery's brochure, the exhibition is explained: "Souad Mardam Bey meditates on contemporary socio-political life.
An elderly British man fell in step alongside Mehmet Bey and Ahmet Bey as they carried his daughter, a solid woman of middle age, in their sedan chair.
The class taught Bey that belief in your ability to lead prepares you for that opportunity.
Back in the Bay Area in the early 1990's, Bailey began covering African-American doings for the Oakland Tribune, sometimes writing positive stories about the Bey family empire built around the bakery, which served simultaneously as a compassionate employer of ex-convicts, a community center, a mosque, and a command post for thuggery.
His first novel, Cevdet Bey and His Sons, was published in 1982.
This article focuses on the education at one specific darulhuffaz in Konya, Turkey, called Darulhuffaz of Nasuh Bey. The purpose of this article is to examine Darulhuffaz of Nasuh Bey's system of education, its charitable foundation, as well as its education based on information available in the Ottoman Archives, in Konya, Ankara, and Istanbul, Turkey.
Bey and Tomas Gallareta, of Mexico's National Institute of Archaeology and History, have previously found that the Maya had inhabited the Puuc region since 500 B.C.
The Prooff brand brings together strands of Bey's work on how product design can transform the workplace.