betulinic acid


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betulinic acid

A natural pentacyclic triterpene extracted from bark of various plants—e.g., Betula pubescens, Lycopus lucidus, Syzigium claviflorum, Ziziphus mauritiana, Prunella vulgaris, and others—which is anti-retroviral (inhibits steps of HIV assembly and virion budding), anti-malarial, anti-inflammatory and anti-proliferative (inhibits telomerase and induces apoptosis).
References in periodicals archive ?
arvensis and betulinic acid as positive control on angiogenic using rat aorta ring assay.
Comparison of the NMR data with those described in the literature, confirmed the identity of these compounds as friedelin (3) [21-23], friedelan-3p-ol (4) [23,24] and betulinic acid (5) [23,25].
Betulinic acid, a potent inhibitor of eukaryotic topoisomerase 1: identification of the inhibitory step, the major functional group responsible and development of more potent derivatives.
The compounds shibuol and betulinic acid found in persimmons are believed to have cancer-fighting properties.
sonneratiodes has hentriacontane, hentriacontanol, b-sitosterol, a-amyrin, epioleanolic acid, epifriedelinol, lignoceryl ferulate, betulinic acid, acacetin, ellagic acid and its tetramethyl ether, quercetin 3-glucoside and 3-galactoside, genkwanin and gentianin 4'-galactoside (Bhakuni et al.
Anti-HIV activity of YK-FH312 (a betulinic acid derivative), a novel compound blocking viral maturation.
Betulinic acid was the major constituent in fraction 3 and exhibited only mild activity ([LC.
PA-457 is synthetic derivative of a natural product, betulinic acid, which is found in the bark of many trees.
Five chemicals in raisins--oleanolic acid, oleanolic aldehyde, betulin, betulinic acid, and 5-(hydroxymethyl)-2-furfural--seem to be responsible for this effect.
Raisins contain oleanolic acid, oleanolic aldehyde, betulin, betulinic acid and 5-(hydroxymethyl)-2-furfural, all of which slow down the growth of bacteria and also stop it sticking to teeth to form plaque, which can make teeth fall out.
Five chemicals in raisins--oleanolic acid, oleanolic aldehyde, betulin, betulinic acid, and 5-(hydroxymethyl)-2-furfural--are thought to be responsible for the protection, at least in the laboratory.