Keywords: Betulinic acid
; Triterpene; Organotin(IV) Complex; Antimicrobial activity; Antioxidant activity.
(3-hydroxy-lup-20 (29)-en-28-oic acid)10 structurally speaking is a pentacyclic lupine type compound belonging to a class named triterpenoid which is distributed broadly in the plant kingdom.
Analyte Mass data [t.sub.R] (min) Ion mode Spinosin 608.1741 2.40 ES[I.sup.-] 6"'-Feruloylspinosin 784.2215 2.54 ES[I.sup.-] Jujuboside A 1207.3533 2.75 ES[I.sup.-] Jujuboside B 1044.5505 2.83 ES[I.sup.-] Camelliaside B 726.2007 2.36 ES[I.sup.-] Betulinic acid
456.3604 5.16 ES[I.sup.-] Analyte M[S.sup.1] (m/z) M[S.sup.2] (m/z) Spinosin 607.10 427.10 6"'-Feruloylspinosin 783.40 427.20 Jujuboside A 1206.60 1073.30 Jujuboside B 1043.60 911.40 Camelliaside B 725.30 284.00 Betulinic acid
455.30 455.30 Analyte DP/V CE/eV Spinosin -26.46 -41.60 6"'-Feruloylspinosin -25.83 -50.92 Jujuboside A -60.00 -60.00 Jujuboside B -27.20 -49.77 Camelliaside B -23.72 -53.07 Betulinic acid
-97.00 -20.00 TABLE 2: Calibration curves, correlation coefficients (r), and linear ranges of the six components.
Therefore, helicteric acid (HA), oleanic acid (OA), and betulinic acid
(BA) were selected for our experiments and extracted from HT according to our previous study .
Borska et al., "The new esters derivatives of betulin and betulinic acid
in epidermoid squamous carcinoma treatment*-in vitro studies," Biomedicine and Pharmacotherapy, vol.
Scheffler, "Solubility studies of oleanolic acid and betulinic acid
in aqueous solutions and plant extracts of Viscum album L," Planta Medica, vol.
fruit extract and quantification of betulinic acid
by HPLC," Phytomedicine, vol.
Water stress (waterlog and drought) increase betulinic acid
and phenolic compounds in Hypericumbrasiliense.
, isolated from Vitis amurensis root, attenuates melanin production by inhibiting tyrosinase, tyrosinase-related protein (TRP)-l and TRP-2 expression through the modulation of their corresponding transcription factors.
is a pentacyclic triterpenoid with reported antiretroviral, antimalarial and anti-inflammatory activity and anticancer properties extracted from the bark of Betula pubescens (53), (54).
Sriram, "Betulinic acid
and its derivatives: a review on their biological properties," Current Medicinal Chemistry, vol.