beta-thalassaemia

beta-thalassaemia

A form of THALASSAEMIA caused by failure to synthesize the beta chains of HAEMOGLOBIN.

be·ta-thal·as·se·mi·a

(bātă thală-sēmē-ă)
Thalassemia due to one of two or more genes that depress (partially or completely) synthesis of beta-globin chains by the chromosome bearing the abnormal gene.
References in periodicals archive ?
The molecular basis of beta-thalassaemia intermedia in southern China: genotypic heterogeneity and phenotypic diversity.
GH response to provocation and circulating IGF-I and IGF-binding protein-3 concentrations, the IGF-I generation test and clinical response to GH therapy in children with beta-thalassaemia. Eur J Endocrinol 1998;138:394-400.
Prevalence of endocrine complications in beta-thalassaemia major in the Islamic Republic of Iran.
Beta-thalassaemia intermedia: Is it possible consistently to predict phenotype from genotype?
Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major.
Prevalence and genotypes of alpha-and beta-thalassaemia carriers in Hong Kong-implications for population screening.
SAFE: The study says gene therapy for patients with beta-thalassaemia can be safe.
Both parties will collaborate to develop EPI01 in sickle cell disease and beta-thalassaemia. EpiDestiny retains all rights to continue development of EPI01 in oncology.
The triplicated alpha-globin gene locus in beta-thalassaemia heterozygotes: clinical, haematological, biosynthetic and molecular studies.
Epidemiology of Transfusion Transmitted Infection among Patients with beta-Thalassaemia Major in Pakistan.
The first report of the Crispr/Cas9 technique being applied to human embryos (http://www.ibtimes.com/worlds-first-genetically-modified-human-embryo-created-chinese-scientists-claim-new-1893752) emerged in April 2015 , when a team of Chinese scientists showed - through a partially successful experiment - that errors in the DNA that cause beta-thalassaemia, a life-threatening blood disorder, could be corrected through gene modification in early stage embryos.