beta-lactamase inhibitors

β-lac·tam·ase in·hib·i·tors

drugs (for example, clavulanic acid) that are used to inhibit bacterial β-lactamases; often used with a penicillin or cephalosporin to overcome drug resistance.

be·ta-lac·tam·ase in·hib·i·tors

(bātă lakti-mās in-hibi-tŏrz)
Drugs used to inhibit bacterial β-lactamases; often used with a penicillin or cephalosporin to overcome drug resistance.
References in periodicals archive ?
Beta-lactamase inhibitors restore or potentiate the activity of beta-lactam antibiotics.
In our search for beta-lactamase inhibitors from natural resources, we found that the methanol extract of the roots of Fissistigma cavaleriei showed an inhibitory effect on beta-lactamase.
The future development of novel beta-lactams resistant to hydrolysis by these versatile enzymes and the discovery of highly potent "second generation" beta-lactamase inhibitors are eagerly awaited.
They ordered beta-lactamase inhibitors second most commonly, in about 30% of prescriptions.
Should a similar resistance phenotype disseminate, it might have strategic implications for the development of new beta-lactamase inhibitors and for selection of beta-lactam compounds to associate wth inhibitors.
for the development and commercialization of small molecule beta-lactamase inhibitors to overcome antibiotic resistance.
Beta-lactamase inhibitors are agents that inhibit bacterial enzymes that destroy beta-lactam antibiotics and result in resistance.
Evaluation of beta-lactamase inhibitors in disk tests for detection of plasmid-mediated AmpC _beta-lactamases in well-characterized clinical strains of Klebsiella spp.
AmpC beta-lactamases are resistant to all marketed beta-lactamase inhibitors.
pneumoniae from Singapore, were resistant to all carbapenems, penicillins and cephalosporins, and these resistance cannot be overcome with any beta-lactamase inhibitors.
Evaluation of PPI-0903 (TAK-599), a Novel Cephalosporin: Bacterial Activity, Effects of Modifying Testing Parameters and Optimization of Disk Diffusion Tests, Saturday, October 30, 1:30 PM, Novel beta- Lactams: beta-Lactamase Inhibitors, Cephalosporins, Carbapenems and Penicillins, H.
Entirely new beta-lactamase inhibitors that kill many of the infectious bacteria that are currently resistant to most of the modern antibiotics.

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