beta-lactam


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Related to beta-lactam: beta-lactamase, Beta-lactam Ring

β-lac·tam

(lak'tam),
A class of broad-spectrum antibiotics that are structurally and pharmacologically related to the penicillins and cephalosporins.

beta-lactam

(bā′tə-lăk′təm, bē′-)
n.
1. A lactam composed of a four-membered ring, formed by intramolecular condensation of an amino acid in which the amino group is located at the beta position, or any compound containing this group.
2. A beta-lactam antibiotic.

be·ta-lac·tam

(bā'tă lak'tam)
Class of broad-spectrum antibiotics structurally and pharmacologically related to penicillins and cephalosporins.
References in periodicals archive ?
These often include beta-lactams, a class of antibiotics that include penicillin and a host of other structurally related compounds.
The proposed Phase 3 study proposes to evaluate the potential efficacy and safety of ribaxamase in a broader patient population by the inclusion of additional IV beta-lactam antibiotics with ceftriaxone and by enrolling patients with a variety of underlying infections.
Based on our institution's antiobiogram, a previous study showing no benefit in Pseudomonas coverage with use of an antipseudomonal fluoroquinolone and antipseudomonal beta-lactam, (7) along with our knowledge of mechanisms of resistance, led us to hypothesize that providing "double coverage" for empiric Pseudomonas coverage with floroquinolones in addition to piperacillin-tazobactam would provide no additional coverage.
Ramsey: The switch from second-line options to beta-lactams saved an estimated $780 per patient and close to $40,000 overall.
MRSA is vulnerable to beta-lactams when the bacterium's ability to make a building block for its cell wall is disabled.
The best evidence right now is that for simple cellulitis (no purulence, abscess, or exudate), treatment with a beta-lactam antibiotic is the best option.
The MaxSignal Beta-Lactam ELISA Test Kit is manufactured to the international quality standard ISO 9001:2008 (ISO CI#: SARA-2009-CA-0114-A).
Continuous infusion of beta-lactam antibiotics in severe sepsis: A multicenter double-blind, randomized controlled trial.
"We have seen truly impressive bacterial eradication in highly resistant strains generated by combination of this beta-lactamase inhibitor with existing beta-lactam antibiotics," commented Christopher G.
The Enterome microbiome study, scheduled for completion in the second half of 2014, is expected to provide a better understanding of the harmful effects of beta-lactam antibiotics on the gut bacterial community.
Empiric combination therapy using a beta-lactam antibiotic plus an aminoglycoside is no more beneficial than empiric monotherapy using an appropriately broad-spectrum beta-lactam antibiotic alone for children suspected of having gram-negative bacteremia, according to a report.
The acquisition includes Orchid's beta-lactam antibiotics manufacturing complex (comprising Cephalosporin, Penicillin and Carbapenem facilities), pharmaceutical research and development facility at Irungattukottai, Chennai and its generic injectable product portfolio and pipeline.

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