acetyl-CoA acyltransferase

(redirected from beta-ketothiolase)

a·ce·tyl-CoA ac·yl·trans·fer·ase

an enzyme catalyzing the thioclastic cleavage by coenzyme A of β-ketoacyl-CoA, forming an acyl-CoA with a carbon chain shorter by two atoms, the missing two atoms appearing as acetyl-CoA. A step in fatty acid degradation.
See also: acetyl-CoA acetyltransferase.
References in periodicals archive ?
The nearest there has been to a diagnosis was when it was suggested he could have beta-ketothiolase deficiency, a rare condition which impairs the body's ability to breakdown fat.