beta-glucuronidase


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beta-glucuronidase

, β-glucuronidase (bāt′ă-gloo″kū-ron′ĭ-dās″)
An enzyme found in lysosomes. It is involved in the breakdown of glycosaminoglycan.
References in periodicals archive ?
In our study, we generally showed statistically significant correlations between increased resistance to 5-fluorocytosine, ketoconazole, miconazole, fluconazole, itraconazole and higher activity of alpha-galactosidase, alpha-glucosidase, leucine arylamidase, beta-glucuronidase, beta-glucosidase, chymotrypsin, esterase, acid phosphatase, alkaline phosphatase, naphthyl phosphohydrolase, N-acetyl-beta-D-glucosidase, and trypsin for isolates from hand surfaces.
Enzymatic analysis of beta-glucuronidase activity in the parents showed results compatible with (though not diagnostic of) a carrier state: 15 nmol/ml/h in the father and 21 nmol/ml/h in the mother (normal range = 11-154 nmol/ml/h, mean = 54nmol/ml/h, and control value = 60 nmol/ml/h).
Evaluation and modification of spectrophotometric procedures for analysis of lactate dehydrogenase, beta-glucuronidase and arylsulphatase in human gingival crevicular fluid collected with filter-paper strips.
Additively and synergistically, the elevated fecal beta-glucuronidase was deconjugating whatever little cytochrome p450 detoxification was taking place, leading to the inability to clear and thus the accumulation of ambient chemicals and internal toxins that could not be oxidized for conjugation; notice the dual effect of endotoxin-mediated blockade of cytochrome p450 along with increased enterohepatic recycling due to the elevated fecal beta-glucuronidase.
Glucuronyltransferase, which converts unconjugated bilirubin to conjugated bilirubin, is thought to be less active in the newborn while conversely the enzyme that converts conjugated bilirubin to unconjugated bilirubin in the intestine (beta-glucuronidase) is thought to be more active (Preer and Phillip, 2011).
The available data suggest that mediators in gingival crevicular fluid identify the acute inflammatory response (neutrophil lysosomal enzymes such as beta-glucuronidase).
Chromogenic substrate in the medium detects the beta-glucuronidase enzyme that is highly specific to E.coli.
and Bevan, M.W., 1987, "GUS fusions: beta-glucuronidase as a sensitive and versatile gene fusion rnarker in higher plants," EMBO J., 6, pp.
Summary A study was undertaken to find out the usefulness of determining the circulating levels of beta-glucuronidase, a lysosomal enzyme in leprosy affected children of less than 15 years of age.
Beta-glucuronidase -- A normal enzyme occurring abnormally in CSF in leptomeningeal carcinomatosis.
This is a preliminary report on the use of a relatively new technique--enzyme-potentiated desensitization (EPD)--that utilizes a mixture of extremely dilute antigens mixed with the enzyme beta-glucuronidase. The method was developed and refined over the past 30 years by McEwen.

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