beta-glucuronidase


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β-glucuronidase

/β-glu·cu·ron·i·dase/ (gloo″ku-ron´ĭ-dās) an enzyme that attacks terminal glycosidic linkages in natural and synthetic glucuronides and that has been implicated in estrogen metabolism and cell division; it occurs in the spleen, liver, and endocrine glands; deficiency results in Sly's syndrome.

beta-glucuronidase

, β-glucuronidase (bāt′ă-gloo″kū-ron′ĭ-dās″)
An enzyme found in lysosomes. It is involved in the breakdown of glycosaminoglycan.

β-glucuronidase

an enzyme which attacks glycosidic linkages in natural and synthetic glucuronides; occurs in the spleen, liver and endocrine glands.

g. deficiency
is the basis for mucopolysaccharidosis type VII in humans, dogs and inbred mice.
References in periodicals archive ?
Both groups of strains showed higher enzymatic activity for alpha-galactosidase, alpha-glucosidase, beta-glucuronidase, beta-glucosidase, chymotrypsin, and naphthyl phosphohydrolase.
lysozyme, beta-glucuronidase and N-acetyl beta-glucosaminidase in adult leprosy correlating the levels with activity of the disease.
Beta-glucuronidase -- A normal enzyme occurring abnormally in CSF in leptomeningeal carcinomatosis.
This is a preliminary report on the use of a relatively new technique--enzyme-potentiated desensitization (EPD)--that utilizes a mixture of extremely dilute antigens mixed with the enzyme beta-glucuronidase.
Because children with the disease lack a functional form of an enzyme called beta-glucuronidase (GUSB), Sands and associates tried to prevent the disorder by using AAV as a viral vector to deliver the GUSB to the mice.
Three of their products, avidin, beta-glucuronidase and aprotinin (a protease inhibitor commonly used by surgeons), have been produced in sufficient quantities to be sold through a commercial chemical supplier, the St.
On-line deconjugation of chloramphenicol-[beta]-D-glucuronide on an immobilized beta-glucuronidase column.
After 3 weeks, the transplanted cells had penetrated diverse regions of the brain and produced beta-glucuronidase, the enzyme that victims of Sly syndrome cannot make.
If beta-glucuronidase levels go unchecked, they may not only reverse glucuronidation but allow toxins to remain in the body to potentially cause cell damage.
It is a lysosomal storage disorder caused by deficiency of an enzyme called beta-glucuronidase, which causes an abnormal buildup of toxic materials in the body's cells.
1 nmol), and the lowest activity of beta-glucuronidase (an average of 0.
Enzyme potentiated hyposensitization II: Effect of glucose, glucosamine, N-acetylaminosugars and gelatin on the ability of beta-glucuronidase to block the anamnestic response to antigen in mice.