The antifungal activity of the plant has been attributed to its hydroxycoumarin content; anti-inflammatory activity to its monoterpenes; bacteriostatic properties to its beta-carboline
alkaloids; antiviral effects to its meliacin and meliacarpin; and insecticidal and antifeedant activity to its limonoids, which belong to the tetranortriterpenoid class of compounds.
Inhibition of monoamine oxidase A by beta-carboline
alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO).
Determination of N,N-dimethyltryptamine and beta-carboline
alkaloids in human plasma following oral administration of Ayahuasca.
alkaloids in Pegannum harmala and inhibition of human monoamine oxidase (MAO).
They describe four different neurochemical models: the filter model, the beta-carboline
and tryptamine model, the DMT model, and the ketamine model.
The study by the Translational Genomics Research Institute (TGen) showed that beta-carboline
alkaloids could potentially be used in therapeutic drugs to stop, or at least slow down, the progressively debilitating effects of Alzheimer's.
Selective inhibition of in vitro synthesis of cancer DNA by alkaloids of the beta-carboline
The contributors, a good mix of academics and industrial experts, cover natural toxicants such as pyrrolizidine alkaloids, glucosinolates, phycotoxins in seafood, mushroom toxins (including edible and toxic mushrooms), mycotoxins, phytoestrogens and beta-carboline
alkaloids as well-as man-made elements such as nitrates and nitrites, acrylamide in heated foods, furan, chloropropanols and their fatty acid esters, hetrocyclic amines and polycyclic aromatic hydrocarbons.
and inhibitory activities of related beta-carboline
This plant contains beta-carboline
alkaloids including harmine, harmaline, and tetrahydroharmine that serve as potent monoamine oxidase inhibitors (MAOIs) (Metzner 2006: 49).
From the behavioral pharmacology of Beta-carbolines
to seizures, anxiety, and memory.