Also found in: Dictionary.
A protein fragment formed by the cleavage of amyloid precursor protein that aggregates into deposits characteristically found in the brains of people with Alzheimer's disease. Also called amyloid beta-peptide, amyloid beta-protein, beta-amyloid peptide, beta-amyloid protein.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
beta-amyloidA4, β—amyloid Neurology A 4 kD polypeptide encoded on chromosome 21 arising from altered processing of amyloid precursor protein, an integral membrane glycoprotein secreted as a truncated carboxyl-terminal molecule; BA forms plaques in the brains of Pts with Alzheimer's disease–AD, Down syndrome, infectious encephalopathy, cerebral amyloid angiopathy; BA is found in skin, intestine, adrenal gland. See Alzheimer's disease, Amyloid, Presenilin. Cf Alpha2-macroglobulin.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.