Combined inhalation of beta-2 agonists
improves swim ergometer sprint performance but not high-intensity swim performance.
It is well documented that due to their excitation effect on the cardiac conduction system, beta-2 agonists
used in the treatment of acute asthmatic attacks frequently increase the incidence of cardiac arrhythmias (8, 27).
Despite years of moderate to high doses of inhaled corticosteroids and beta-2 agonists
, they still suffered episodes of dyspnea, expectoration, coughing, wheezing, chest tightness more than two times a week, and waking up at night with asthma symptoms more than two times a week.
Although the guidelines suggest that all asthmatics should have access to a rescue medication, fewer than 40 percent of the Medicaid patients received an inhaled short-acting beta-2 agonist
during the study year.
The American Academy of Allergy and Immunology has been concerned that media reports which question the use of beta-2 agonists
to treat asthma have caused great anxiety among asthmatics and the public.
For decades, inhaled beta-2 agonists
were strongly associated with adverse cardiac effects in COPD patients with pre-existing cardiovascular disease and an increased risk of CHF decompensation (adjusted OR 3.42; 95% CI 1.99 to 5.86), also with all-cause mortality in patients with CHF (60).
Systematic review and economic analysis of the comparative effectiveness of different inhaled corticosteroids and their usage with long-acting beta-2 agonists
for the treatment of chronic asthma in children under the age of 12 years.
The guideline addresses the use of numerous medications, alone or in combination, including short- and long-acting beta-2 agonists
, short- and long-acting muscarinic antagonists, inhaled corticosteroids, inhaled long-acting anticholinergics, long-term macrolides, oral and IV systemic corticosteroids, roflumilast (when chronic bronchitis is present), oral slow-release theophylline, oral N-acetylcysteine, oral carbocysteine, and statins.
Both groups were given the same basic medication, including inhaled glucocorticoids and beta-2 agonists
. In addition, those in the treatment group were given a herbal paste (components below), and told to take 25g orally (with warm water) twice a day for 60 days (beginning from the winter solstice).
He identified those athletes with documented asthma and AHR from among those who during the last five Olympic games -from 2002 to 2010- used inhaled beta-2 agonists
(IBA), a drug frequently used by elite athletes as an anti-asthma treatment.