ADRB2

(redirected from beta-2 adrenergic receptor)

ADRB2

A gene on chromosome 5q31-q32 that encodes beta-2-adrenergic receptor, a member of the G protein-coupled receptor superfamily, which mediates catecholamine-induced activation of adenylate cyclase. ADRB2 binds epinephrine with a 30-fold greater affinity than it does with norepinephrine.
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Beta-2 adrenergic receptor genetic polymor-phisms and asthma.
Genetic polymorphisms of the beta-2 adrenergic receptor in Israelis with severe asthma compared to non-asthmatic Israelis.
Flucatisone is a corticosteroid and salmeterol is a selective long-acting beta-2 adrenergic receptor agonist.
Stimulation of the former increases maternal heart rate and stroke volume, whereas stimulation of the beta-2 adrenergic receptors causes the relaxation of smooth muscle, including the muscles of the myometrium, blood vessels, and bronchial tree.