ADRB1

(redirected from beta-1 adrenergic receptor)

ADRB1

A gene on chromosome 10q24-q26 that encodes beta-1-adrenergic receptor, a member of the G protein-coupled receptor superfamily, which mediates catecholamine-induced activation of adenylate cyclase. ADRB1 binds epinephrine and norepinephrine with the same affinity.
References in periodicals archive ?
Shamloo, "Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer's disease using a biased and selective beta-1 adrenergic receptor partial agonist," Neuropharmacology, vol.
The investment was triggered by the excellent progress made both by HTL's in-house team and by its founding scientists at the MRC Laboratory of Molecular Biology, Cambridge, who have recently solved the structure of the beta-1 adrenergic receptor based on their novel GPCR-stabilisation methodology.
Histologically, beta-2 adrenergic receptors are located primarily within bronchiole smooth muscle; beta-1 adrenergic receptors are located within the cardiovascular system.