beta subunit


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beta subunit

Glycoprotein hormones containing two different polypeptide subunits designated α and β chains. Analysis of the units of these hormones (e.g., follicle-stimulating, luteinizing, chorionic gonadotropin, and thyrotropin) enables early diagnosis of such conditions as pregnancy and ectopic pregnancy.
References in periodicals archive ?
The amplification results of Murrah buffalo PHB, CAPZB, TEKT2 coding sequnence (CDS).PHB, prohibitin;CAPZB, capping actin protein of muscle Z-line beta subunit; TEKT2, tektin-2; PCR, polymerase chain reaction.
Caption: Figure 3: Representative images of Western blotting evaluating the expression of translationally controlled tumor protein (TCTP) (a), ATP-specific succinyl-CoA synthetase beta subunit (SUCLA2) (b) in the hippocampus, and gamma-enolase isoform 1 (NSE) (c) in the cortex from STZ-treated (STZ) and control (CTL) mice.
Mesut et al., "A novel splice site mutation of the beta subunit gene of epithelial sodium channel (ENaC) in one Turkish patient with a systemic form of pseudohypoaldosteronism type 1," Journal of Pediatric Endocrinology and Metabolism, vol.
The similarity in the chemical structure of the beta subunits of hCG and LH have been reported as false-positive tests in the absence of pregnancy.
The diagnosis was confirmed by detection of a homozygous pathogenic mutation (c.1173dupT) in the PCCB (propionyl-CoA carboxylase beta subunit) gene.
CD122, which is known as the Interleukin-2 (IL-2) receptor beta subunit, is a key signaling receptor that is known to increase the proliferation of CD8-positive effector T cells.
That study, which employed standard molecular cloning techniques to screen a cDNA library prepared from mRNA of isolated cnidocytes of Physalia physalis, revealed the presence of voltage-gated [Na.sup.+], [K.sup.+], and [Ca.sub.2+] channels, together with a [Ca.sup.2+] channel beta subunit. The K+ channel ([PpK.sub.V]1) and [Ca.sup.2+] beta subunit (Pp[Ca.sub.V][beta]) were cloned in their entirety and functionally expressed.
To further add to the complexity of the system, there are three allelic variants of the beta subunit designated [[beta].sub.1], [[beta].sub.2], and [[beta].sub.3] and two allelic variants of the gamma chain designated [[gamma].sub.1] and [[gamma].sub.2], giving rise to, respectively, ADH1B*1, ADH1B*2, ADH1B*3, ADH1C*1, and ADH1C*2.
A kit for the quantification of the free beta subunit of chorionic gonadotropin (hcg beta beta) in the serum of pregnant women, wash buffer (1pc x 250ml), maternal control serum for monitoring the accuracy of studies in the first trimester of pregnancy, a set of reagents for the quantitative determination of placental protein a in the serum of pregnant women, strengthening solution (1pc x 250ml)
eCG is composed of two dissimilar subunits, alpha and beta subunit consisting of 96 and 149 amino acids, respectively.
MADD may be caused by mutations in the electron transfer flavoprotein alpha subunit (ETFA), [4] electron transfer flavoprotein beta subunit (ETFB), or electron transfer flavoprotein dehydrogenase (ETFDH) genes.
The single chain of 145 amino acids that comprises the beta subunit is unique to hCG; the alpha subunit is common to other members of the family of glycoprotein hormones to which hCG belongs, including LH, FSH, and TSH.