berberine


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ber·ber·ine

(ber'ber-ēn),
An alkaloid from Hydrastis canadensis (family Berberidaceae); has been used as an antimalarial, antipyretic, and carminative, and externally for indolent ulcers.

berberine

(bûr′bə-rēn′)
n.
A bitter, yellow alkaloid, C20H19NO5, obtained from several plants such as goldenseal and having medical uses as an antipyretic and antibacterial agent.

berberine

Herbal medicine
A nonaqueous bitter alkaloid abundant in the rhizomes and roots of goldenseal (Hydrastis canadensis and barberry, which is amebicidal, antibacterial (used to treat cholera), antimalarial, antipyretic, sedative, a gastic tonic and possibly antihypertensive.

ber·ber·ine

(bĕr'bĕr-ēn)
An alkaloid fromHydrastis canadensis; has been used as an antimalarial, antipyretic, and carminative, and externally for indolent ulcers.
References in periodicals archive ?
Fruit fluorescing under laser-scanning confocal microscope Leica TCS SP-5 (laser excitation 405 nm): ((a) and (b)) single cells of fruit border on transverse slice, bar = 30 [micro]m, (c) excretion from the fruit, (d) the fluorescence spectra from (b) (cells emitted in green- yellow are marked by rings) and (c) images, (e) the fruit pulp, (f) secretory hair, (g) the fluorescence spectra from images (e) and (f), and (h) the fluorescence spectra registered by spectrofluorometer Perkin Elmer 350 MPF-44B in 0.5 [cm.sup.3] cuvette from water solution of [10.sup.-5] M berberine. Flower: ((i) and (j)) images of whole flower and pistil with pollen on the pistil stigma done by stereomicroscopy and (k) the fluorescence spectra of pollen and pistil recorded by microspectrofluorimetry.
Mixing HA with CMC not only delays the absorption of HA but also prolongs the duration of the antimicrobial and anti-inflammatory effects of HA and berberine [35, 36].
Li, "Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors," Bioorganic & Medicinal Chemistry, vol.
Zhou, "Inhibitory effects of berberine on ATP-sensitive K+ channels in cardiac myocytes," European Journal of Pharmacology, vol.
(2013) reported that berberine down-regulated EGFR expression through enhancing Cb1 ligase activity, an ubiquitin ligase belongs to E3 ubiquitin ligases family, which is tyrosine phosphorylated, resulting in ubiquitinylation of EGFR and its translocation to endosomal compartment.
Berberine stabilizes the mRNA of liver LDL receptor (by the activation of AMP-activated protein kinase (AMPK), the inhibition of mitogen-activated protein kinase MAPK) and modulatory effects on PPAR-gamma and alpha (Brusq et al.
And in animal trials conducted with rabbits, mice and rats, berberine inhibited the growth of E.
Berberis lycium has known to possess berberine, berbamine, palmitine and [beta]-sitosterol as major constituents and these phytochemicals have been validated for anti-inflammatory activities in several studies (Li et al., 1999; Liu et al., 2010; Loizou et al., 2010, Singh et al., 2010).
Next, we discuss the following phytochemicals: quercetin, berberine, genistein, kaempferol, and curcumin (Figure 3).
Several studies have been conducted on its biological activities and more specifically on berberine, an isoquinoline alkaloid, considered as an active molecule with many properties such as hypoglycemic, antibacterial, antifungal, anti HCV, and anticancer activities [2-8].