Surfactant (Survanta,(R) Abbott Laboratory, Chicago, IL) used in the study was given by intratracheal route, 100mg of beractant phospholipids/kg birth weight/dose (4mL/kg/dose), as per manufacturer's instructions and standard protocol.
Complications among premature neonates treated with Beractant and Poractantalfa.
With this, the DOH has been taking advantage of the funds to purchase beractant
and surfactanta treatment for respiratory distress syndrome (RDS) acquired by pretermsfor 2014 and 2015.
23) in which proctant alpha was given to one group of patients with RDS and beractant
was given to another group, it was found that the requirement for a second dose of surfactant was lower, extubation occured earlier, oxygen requirement was lower, but the rate of BPD was higher in the proctant alfa (Curosurf[C]) group compared to the beractant
(Survanta[C]) group and the morbidity and mortality rates were similar in both groups.
In the study, the infants were treated with lucinactant (Surfaxin), colfosceril palmitate (Exosurf), or beractant
(Survanta) within 30 minutes of birth.
Baroutis y colaboradores (12) compararon el regimen con tres surfactantes naturales: alveofact, poractant y beractantes
, en recien nacidos prematuros con SDR, y llegaron a la conclusion de que los dos primeros tipos de surfactante generaron menos dias de ventilacion, menos dias de suministro de oxigeno y menor estancia hospitalaria comparados con el grupo de beractant
The results concluded that KL-4 surfactant reduced inflammation and cell injury, resulting in improved cell survival and function compared with both a saline control as well as beractant
(Survanta(r)), an animal-derived surfactant and currently the most frequently prescribed surfactant in the United States.
The marketers of Curosurf (Chiesi Farmaceutici SpA in the European Union and Dey Laboratories, LP in the USA) have sponsored a series of small clinical trials that have compared the acute response of patients to prophylactic treatment at birth with poractant alfa or beractant
Lioresal baclofen Treatment of intractable Intrathecal spasticity caused by spinal cord injury, multiple sclerosis, other spinal diseases Lupron injection leuprolide acetate Treatment of central Prolastin alpha-1 -proteinase precocious puberty inhibitor (human) Replacement therapy in the alpha-1 -proteinase inhibitor congenital deficiency state Survanta beractant
Prevention and treatment of intratracheal neonatal respiratory suspension distress syndrome.
Use of poractant with an initial dose of 200 mg/kg resulted in more decrease in requirement of oxygen compared to beractant
in preterm babies with RDS below the 35 gestational week.
Examples of natural surfactant include Beractant
(Survanta), Poractant Alfa (Curosurf), and Clafactant (Infasurf)
Birimimizde dogum odasinda entubasyon gereksinimi olan 30 haftaliktan kucuk bebeklere ilk 15 dakika icinde surfaktan uygulanirken, 30 haftanin ustundeki bebeklere erken kurtarma tedavisi seklinde ilk iki saat icinde 100/mg/kg dozunda beractant