Examples of CCBs include bepridil
(Vasocor[R]), amiodipine besylate (Norvasc[R]), and verapamil hydrochloride (Calan SR[R]).
Evaluation of drug-induced QT interval modifications in dynamic electrocardiography: the case of bepridil
. Fundam Clin Pharmacol 1993;7:61-8.
Pyrrolidine also known as tetrahydropyrrole--an organic compound found naturally in the plants--is used as pharmaceutical drugs such as procyclidine and bepridil
(anticholinergic) for the treatment of Parkinsons disease, acute dystonia, and akathisia syndrome .
Kuptsova et al., "Non-selective calcium channel blocker bepridil
decreases secondary pathology in mice after photothrombotic cortical lesion," PLoS ONE, vol.
AFib is often initially treated with antiarrhythmic drugs, such as amiodarone (Cordarone, Pacerone), bepridil
hydrochloride (Vascor), or disopyramide (Norpace).
, clinidipine, clevidipine, diltazem, fendilinem,
Among the substances that passed the test were three drugs that are already on the market to treat various diseases: a medication for angina pectoris (bepridil
), one for heart rhythm problems (amiodarone) and the widely used malaria drug chloroquine.
Effects of two Ca-entry blockers bepridil
and nitredipine on isolated vessels.
* tetralols (such as bepridil
, which is no longer sold in the US).
Patients taking Sustiva should not take Hismanal (astemizole), Vascor (bepridil
), Propulsid (cisapride), Versed (midazolam), Orap (pimozide), Halcion (triazolam), or ergot derivatives (for example, Wigraine and Cafergot).
On January 31 the FDA announced that the Sustiva (efavirenz) package insert had been changed "to include drug-drug interaction information regarding coadministration of efavirenz with rifampin, diltiazem, itraconazole, voriconazole, atorvastatin, pravastatin, simvastatin, pimozide and bepridil
(7) When cases of TdP were analyzed by individual medication, the observed prevalence in women was greater than that in men for quinidine, disopyramide, amiodarone, sotalol, bepridil
, and prenylamine (P < .05).