benzonatate


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benzonatate

 [ben-zo´nah-tāt]
an antitussive that depresses cough without affecting respiration, by anesthetizing stretch receptors in the respiratory passages, lungs, and pleura. It is administered orally in capsule or tablet form, but should not be chewed or dissolved in the mouth because the local anesthetic action may cause numbness of the oral mucosa.

ben·zo·na·tate

(ben-zō'nă-tāt),
An antitussive agent related chemically to tetracaine; thought to act by depressing mechanoreceptors in the lungs.

benzonatate

/ben·zo·na·tate/ (ben-zo´nah-tāt) an antitussive that reduces the cough reflex by anesthetizing the stretch receptors in the respiratory passages, lungs, and pleura.

benzonatate

[benzō′nətāt]
a nonopiate antitussive.
indication It is prescribed to suppress the cough reflex.
contraindication Known hypersensitivity to this drug prohibits its use.
adverse effects Hypersensitivity reactions, such as bronchospasm, laryngospasm, and cardiovascular collapse, may occur and may be serious. Vertigo, sedation, headache, and constipation may sometimes occur.

ben·zo·na·tate

(ben-zō'nă-tāt)
Antitussive related chemically to tetracaine.

benzonatate (benzon´ətāt´),

n brand name: Tessalon;
drug class: antitussive, nonnarcotic;
action: inhibits cough reflex by anesthetizing stretch receptors in respiratory system;
uses: nonproductive cough relief.

benzonatate

a non-narcotic antitussive drug that depresses cough without affecting respiration.
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References in periodicals archive ?
In the past, patients would receive 2 100-mg benzonatate perles, which they kept on the tongue until the perles dissolved.
9 ml * Benzocaine/tetracaine spray 2-sec spray Benzonatate 200 mg * When tetracaine is administered via an atomizer for nasal anesthesia, only 0.
Our oral-solid ion exchange resin benzonatate formulation has been shown to reduce or eliminate the choking hazard associated with this effective non-narcotic cough suppressant," said Alitair President and CEO, William W.
Overcoming this significant safety hurdle may be the key to benzonatate becoming a successful Rx-to-OTC switch candidate," continued Howard.
Our proprietary technology allows us to bind benzonatate to a resin particle, which represents a completely novel formulation approach and resolves this significant safety issue.
That left Ascend to supply the entire market at a time when several dynamics conspired together to dramatically increase the demand for benzonatate.
The patent includes the potential of the resin-formulated drug in decreasing or eliminating the choking hazard, which is connected with conventional liquid formulations of benzonatate.
Products launched in the past nine months include Nizatidine oral solution, Amneal's first exclusive or first-to-file generic; Tramadol/APAP tablets and Lorazepam oral concentrate, both controlled substances; Spironolactone HCl tablets; and Benzonatate soft gel capsules.
While the company's current line is small, consisting of ibuprofen, allopurinol, SSD 1% cream, oxcarbazepine and benzonatate, it expects additional approvals shortly and has a strong development pipeline.
Recent approvals include paroxetine tablets, bioequivalent to GSK's Paxil; benzonatate (100- and 200-mg) capsules, bioequivalent to Forest Laboratories Inc.
5,1 and 2 mg, tablet, oral, 100; amiloride hydrocholoride, hydrochlorothiazide EQ 5 mg anhydrous 50 mg, tablet, oral 100; amitriptyline hydrochloride 150 mg, tablet, oral 100; ampicillin/ampicillin trihydrate 250 and 500 mg, capsule, oral, 100; benzonatate 100 mg, capsule, oral, 100; bumetanide 1 and 2 mg, tablet, oral, 100; cholestyramine EQ 4 gm resin/packet, powder, oral, 60; cyclobenzaprine hydrochloride 10 mg, tablet, oral, 100; minocycline hydrochloride EQ 50 and 100 mg base, capsule, oral; temazepam 15 and 30 mg, capsule, oral, 100; tolazamide 250 mg, tablet, oral, 100; and verapamil hydrochloride 240 mg, tablet, extended-release, oral, 100.
has given the former exclusive North American marketing rights to the latter's gelcap forms of benzonatate cough remedy and valproic anti-seizure medication.