Of 30 participants who developed bladder cancer during the trial, 28 had been exposed to benzidine
on the job and two had not.
Cancer incidence and mortality among beta-naphthylamine and benzidine
dye workers in Moscow.
Clearly class 1 carcinogens such as asbestos, benzene, benzidine
, and dioxin merit very high priority in cancer control.
The reaction was developed with a mixture of diamino benzidine
and 30% hydrogen peroxide (Sigma).
The compound 4,4[prime]-bisazidodiphenyl was prepared by diazotation of benzidine
and treatment with Na[N.
2) The FDA calculated in 1985 that ingestion of free benzidine
raises the cancer risk to just under the "concern" threshold (1 cancer in 1 million people).
in 5 mol/l glacial acetic acid, 10% [H.
Arylamine chemicals such as benzidine
, [beta]-naphthylamine, and 2-aminofluorene can also be acetylated by NAT2.
1999) and the aromatic amines benzidine
and 4-aminobiphenyl (Zenser et al.
of monitors Air pollutant Cancer Chronic Cancer Chronic risk risk risk risk Nickel compounds X X Manganese compounds X Cadmium compounds X X 6 Titanium tetrachloride X 2,4-Dinitrotoluene X Methyl tert-butyl ether X 1 1,3-Dichloropropene X Chloroform X 16 Methylene chloride X (dichloromethane) p-Dichlorobenzene X Propylene oxide X Tetrachloroethylene X 16 (perchloroethylene) Trichloroethylene X 1,1,2-Trichloroethane X 16 Bis(2-ethylhexyl)phthalate X Epichlorohydrin X (1-chloro-2,3-epoxypropane) Lead compounds X 1,2-Dibromo-3-chloropropane X 1,4-Dioxane X 2,4-Toluenediamine X Acrylamide X Benzidine
X Dichloroethyl ether X Bis(2-chloroethyl)ether Polycyclic organic matter X Data source AQS 2004 (b) No.
Previous color reagents, benzidine
and aminobiphenyl, were unstable or carcinogenic; Dr.
and safrole, there was a notable sex difference, with high liver tumor incidence observed for early postnatal exposures of male, but not female, mice.