benzamide


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Related to benzamide: benzanilide

benzamide

A crystal obtained by the action of ammonia on benzoyl chloride. Chemical derivatives of benzamide are used in a wide range of therapeutics including analgesics (e.g., salicylamide), antiemetics (e.g., metoclopramide), antipsychotics (e.g., sultopride) and other agents.

benzamide

(ben-zam′īd″) [ benzoin + amide]
Any of a class of drugs, including domperidone, metoclopramide, and trimethobenzamide, that block dopamine and serotonin receptors and stimulate acetylcholine receptors in smooth muscle. They are principally used to treat nausea and vomiting.
References in periodicals archive ?
The aromatic compounds used were 4-nitrophenol, 2aminobenzoic acid, benzamide, 4-aminobenzoic acid, resorcinol, o-bromonitrobenzene and 2-nitroaniline as coupling partners (Scheme I and II).
Coyne et al (31) transplanted marrow stromal cells (MSCs) double-labelled with BrdU and bis- benzamide (BBZ) into the adult hippocampus or striatum noticed that BrdU labelling was colocalized to host phagocytes, astrocytes, and neurons in both regions.
2,5-Dihydroxy-N-(2-hydroxyethyl)benzamide 1a, 2,4-dihydroxy-N-(2-hydroxyethyl) benzamide 1b (Aldrich) and other chemicals and solvents were used as received.
Specific activation of puff 93D of Drosophila melanogaster by benzamide and the effect of benzamide on the heat shock induced puffing activity, Chromosoma 81:125-136.
Cisapride is a substituted benzamide compound that stimulates motor activity in all segments of the gastrointestinal tract by enhancing the release of acetylcholine from the enteric nervous system Actions at enteric neuronal serotonin (5-hydroxytryptamine-[5-HT]) receptors have been implied in the prokinetic effects of cisapride.
The compounds 1 treatment with amino benzyl amine and amino benzamide in boiling benzene or toluene gave the corresponding pyrazole-3-carboxamides 6,7 as main products.
2) Over the years, there has been considerable reduction in the incidence of PONV with the introduction of antiemetic prophylaxis like anti-cholinergics (Scopolamine), anti-histaminics (Diphenhydramine, cyclizine, promethazine, prochlorperazine), butyropheneones (Droperidol), and benzamide (Metoclopramide).
Although protection was less than desirable during weeks 2 and 4 (less than 80%), some short-term protection against biting sand flies was obtained and will supplement other personal protective measures in the field (N,N-Diethyl-3-methyl benzamide (deet) skin repellent, permethrin-treated bed nets and uniforms).
5 wt% triglycidyl isocyanurate in the presence of catalytically acting amines or salts [28], and a variety of N,N-diglycidyl substituted benzamide, aniline, diimide or imidazolone compounds [29].
Tahir, N-(4-Ferrocenylphenyl) benzamide, Acta Crystallographica Section E, m831, E66 (2010).
Although Benzamide derivatives like Metoclopramide accelerates gastric emptying and increases lower oesophageal sphincter tone in non-pregnant patients, their efficacy in doing so is not clear in pregnant patients.
Topical repellents constitute a wide array of chemicals ranging from natural botanicals such as citronella to synthetically derived N,N-Diethyl-3-methyl benzamide (deet).