benign mimic

benign mimic

A generic term for a benign condition that mimics a malignancy, either clinically, by imaging or pathologically.

Benign mimics in pathology
• Atypical adenomaous hyperplasia—mimics prostate cancer.
• Florid endocervical glandular hyperplasia with intestinal and pyloric gland metaplasia—mimics adenoma malignum.
• Mastocytosis—mimics malignant osteoblastic metastases.
References in periodicals archive ?
Sinonasal Paraganglioma (SP) is also a benign mimic of ONB which also exhibits a nesting pattern of tumor cells with positive neuroendocrine expression and surrounding S100 positive sustentacular cells.
Xanthogranulomatous sialadenitis, a benign mimic of malignancy.
Florid endocervical glandular hyperplasia with intestinal and pyloric gland metaplasia: worrisome benign mimic of "adenoma malignum".
Finally, 7% of the participants favored a benign mimic of PIN, including basal cell hyperplasia (3.
It may not be cost-effective to routinely perform IHC for the purpose of differentiating precancers and cancers from their benign mimics, because the latter can be excluded using morphology in the majority of cases.
It emphasizes the morphologic features and immunohistochemistry of biopsies of the cervix, endometrium, and myometrium, as well as differential diagnosis and benign mimics of tumors.
Prostatic Adenocarcinoma and its Mimics: A Practical Approach to Diagnosis Gleason Grading and Reporting of Prostatic Adenocarcinoma: A Contemporary Approach Benign Mimics of Urinary Tract Tumors Classification of Renal Epithelial Neoplasms - New Entities and Diagnostic Challenges Classification and Reporting of Urothelial Tumors - The Good News David Grignon, MD
Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimics.
The many benign mimics makes this criterion especially difficult, particularly for pathologists who see few endometrial biopsies.
Unlike AMACR, which can be negative in about 20% of unequivocal PCa; is positive in a subset of benign mimics of PCa, including adenosis and partial atrophy; and may show focal staining in up to 20% of morphologically benign glands, (29-31) our results here confirm that ERG staining is highly specific for PCa and is exceedingly rare in benign glands (including mimickers of PCa).
In recent years, in addition to consulting on medical cases referred by pathologists, this group has published several articles on the differentiation of DMM from benign mimics.
Hence, the importance of recognizing this variant of urothelial carcinoma and distinguishing it from its benign mimics such as NA, especially in small biopsy specimens, cannot be overemphasized.
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