benign lymphadenopathy

benign lymphadenopathy

A generic term for any non-malignant regional or generalised enlargement of lymph nodes, which is divisible into histologic patterns. These may include: variably sized germinal centre; polarity of germinal centre; absence of capsular or fat invasion; mitotic activity confined to the germinal centre; cortical localization of germinal centre; or inhomogeneous distribution of follicles.

benign lymphadenopathy

Any non-malignant regional or generalized enlargement of lymph nodes. See Lymph node necrosis.
References in periodicals archive ?
Florid follicular hyperplasia, the initial morphology seen in progressive HIV-related benign lymphadenopathy, is characterized by large, irregularly shaped geographic follicles, covering up to two-thirds of the cross-sectional area of the lymph node, surrounded by an attenuated to absent mantle cell zones (Figure 1).
The progressive stages of HIV-related benign lymphadenopathy (FFH [right arrow] MX [right arrow] FI [right arrow] lymphocyte depletion) correlate with the immune status of the patient and parallel the progressive loss of CD4+ T cells, increasing viral load, and collapse of the immune system.
Human herpesvirus-8 DNA sequences in human immunodeficiency virus-negative angioimmunoblastic lymphadenopathy and benign lymphadenopathy with giant germinal center hyperplasia and increased vascularity.

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