benign fibrous histiocytoma


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Related to benign fibrous histiocytoma: malignant fibrous histiocytoma

benign fibrous histiocytoma

A benign tumour composed of primitive mesenchymal cells (macrophages or histiocytes) seen in the skin and soft tissues of the legs of young to middle-aged patients, more commonly women, usually in relation to skeletal muscle.
 
Management
Excision.
References in periodicals archive ?
The histogenesis and classification of fibrohistiocytic lesions involving bone and containing an admixture of fibrous tissue, foam cells, and giant cells are confusing and include several overlapping entities, such as metaphyseal fibrous defect, nonossifying fibroma, fibrous cortical defect, fibroxanthoma, and benign fibrous histiocytoma (BFH) of bone.
The term xanthoma or fibroxanthoma is often given to the latter lesions which (we) consider to be within the broad category of benign fibrous histiocytoma.
Bertoni et al (2) attempted to exclude from their 1988 series any lesions showing definite histologic evidence of "metaphyseal fibrous defect, benign fibrous histiocytoma, aneurysmal bone cyst, simple bone cyst, fibrous dysplasia, osteomyelitis, histiocytosis X, a storage disease, hyperlipoproteinemia, or giant cell tumor.
Genetically all DFSPs express CD34 which has been used to distinguish it from Benign Fibrous Histiocytoma (4) Causation is not clear, chromosomal aberrations may contribute to the etiology.

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