A large, round and strongly basophilic
nucleolus was centrally located in the nucleus with five or six circular nucleoli peripherally situated.
Most of the research on Rickettsia (or RLO) in bivalves describes intracellular, basophilic
inclusions (microcolonies), not associated with severe tissue damage (Comps et al.
(b) Ampullary biopsy (x100) showing submucosal Brunner's glands showing nucleomegaly with eosinophilic intranuclear and basophilic
cytoplasmic inclusion bodies (pointed black arrow) of CMV.
We regard the above-mentioned "basophilic
stippling" of villous basement lamina a nonspecific finding which is usually positive for iron; hence we call it ferrugination .
Burton's lines and basophilic
stippling on a blood smear are some of the more specific symptoms (2).
Small perforating tunnels on the epidermis were filled with keratotic plugs, which were composed of keratin material and degenerated basophilic
Histopathology typically shows horn cysts, tumor islands composed of basophilic
cells of basaloid appearance arranged in peripheral palisading pattern.4,5
Eosinophilic acellular material in cyst of which texture consisting of basophilic
amorphous material were detected on the pathological examination of the specimen taken by fexible bronchoscopy.
The blood test conducted in our ED revealed hypochromic microcytic anemia with basophilic
stippling of the erythrocytes, decreased hemoglobin concentration of 9.4 g/dL, and hematocrit level of 27.9%.
A case of acute basophilic
leukemia with a t(9;22) has been described in the literature.
Many cases of MDS transform to acute myeloid leukemia (AML) , but AML with basophilic
differentiation has been rarely reported.
Microscopically, one of the fragments corresponds to fibroconnective tissue compressed by nodular and lobulated tumour composed of hyaline cartilaginous, without cellular atypia and with basophilic
areas (Figures 1 and 2(A)).